ASD

GO:0032956 regulation of actin cytoskeleton organization (131)

GeneInput weightStandardRank
PFN1--74
SFRP1--204
CDK5R1--406
PFN2--431
TAC10.251543
ARPC1A--545
ACTR3--573
ARPC2--578
SLIT2--582
PARK20.251634
NEBL--685
SHROOM2--763
AMOT--933
CAPZB--953
PROX1--962
RHOA--973
RICTOR--1074
RAC1--1087
DLC1--1105
ARPC5L--1162
SPTBN4--1223
DMTN--1226
EP300--11256
TMSB10--1299
SPTBN2--11344
KANK1--1493
SMAD3--1541
ADD2--1685
BAIAP20.2511725
ARPC4--1795
TSC10.2511844
ARPC1B--1861
ARPC5--1882
VANGL2--1957
SPTAN1--12078
TMSB15A--2105
SPTB--2288
ARPC3--2337
TMSB15B--2402
CAPZA2--2428
CAPZA1--2513
SSH2--2515
FZD10--2606
S1PR1--2910
ILK--2917
LATS1--3031
NEB--3478
LIMK1--3487
JAM3--3978
ACTR3B--4019
SPTA1--14158
RASA1--4166
TMSB4X--4291
ARF6--4366
DIXDC1--4469
ARHGAP6--4472
WNT11--4528
NCK2--4595
PDGFA--4678
NF2--14798
CAPZA3--5405
RDX--15514
CELSR1--5539
PAK1--5556
CCDC88A--5761
SPTBN5--5948
GRHL3--6732
MAP3K1--16751
CCL11--7037
CXCL12--7204
MLST8--7510
TACR1--7688
KISS1R--8159
SPTBN1--8272
TMSB4Y--8925
DSTN--9088
ADD1--19458
SSH1--9532
PDXP--9557
EDN1--9566
RHOC--9929
AVIL--10360
NCK1--10453
DLG1--10557
CAV3--110580
CAPG--10638
SCIN--11105
CORO1A--11557
TMSB4XP8--12337
CDC42EP5--12367
ARHGEF10--12556
ARHGEF19--12571
MYLK3--12912
TWF1--14449
WASH2P--14471
SORBS3--14540
PRKCQ--14566
JMY--14571
F2RL1--15088
RHOQ--15107
MTOR--15435
ACTR3C--15493
WASH6P--16214
CCL24--17974
WASH3P--18486
WASH4P--18575
TMSB4XP4--18618
CCL21--19130
CDC42EP2--19516
CCL26--19975
GPR65--20238
WASH1--20505
PDGFRB--21054
CCR7--21314
TWF2--21814
GSN--122198
VIL1--22201
ARHGEF10L--22238
SDC4--22313
PLEK--22429
LRP1--22904
VILL--23074
NCKAP1L--23440
TPM1--123549
LIMA1--24245
BAIAP2L1--24533
FHOD1--24644
TRIOBP--124727
SYNPO--24784
SSH3--25349
ARAP1--25493

Network

GO:0032956

Network
Enrichment
NameDescriptionExternal IDs
PFN1profilin 1 Entrez:5216  Ensembl: ENSG00000108518  HGNC: 8881  HPRD: 01452 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
CDK5R1cyclin-dependent kinase 5, regulatory subunit 1 (p35) Entrez:8851  Ensembl: ENSG00000176749  HGNC: 1775  HPRD: 04586 
PFN2profilin 2 Entrez:5217  Ensembl: ENSG00000070087  HGNC: 8882  HPRD: 01451 
TAC1tachykinin, precursor 1 Entrez:6863  HGNC: 11517  HPRD: 08876  Ensembl: ENSG00000006128 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PFN1profilin 1
SFRP1secreted frizzled-related protein 1
CDK5R1cyclin-dependent kinase 5, regulatory subunit 1 (p35)
PFN2profilin 2
TAC1tachykinin, precursor 1
Query geneGeneGene descriptionEdge score
PFN1PFN1profilin 1
SFRP1SFRP1secreted frizzled-related protein 1
CDK5R1CDK5R1cyclin-dependent kinase 5, regulatory subunit 1 (p35)
PFN2PFN2profilin 2
TAC1TAC1tachykinin, precursor 1

Troyanskaya Laboratory - Princeton University