ASD

GO:0051494 negative regulation of cytoskeleton organization (70)

GeneInput weightStandardRank
MAPT0.25131
MAP2--98
STMN2--221
MAPRE1--296
MAP1B--300
SNCA--1401
PFN2--431
CLASP2--487
APC0.251528
SLIT2--582
PARK20.251634
CLIP3--739
SHROOM2--763
CAPZB--953
DLC1--1105
SPTBN4--1223
DMTN--1226
TMSB10--1299
SPTBN2--11344
CLASP1--1481
KANK1--1493
ADD2--1685
SPTAN1--12078
TMSB15A--2105
SPTB--2288
TMSB15B--2402
CAPZA2--2428
CAPZA1--2513
ARHGEF2--2743
INPP5J--2851
S1PR1--2910
SPTA1--14158
TMSB4X--4291
ARHGAP6--4472
STMN1--4584
KATNB1--5389
CAPZA3--5405
RDX--15514
SPTBN5--5948
MAP3K1--16751
TBCD--6876
SPTBN1--8272
MID1IP1--8619
TMSB4Y--8925
ADD1--19458
ESPN--19799
AVIL--10360
TRIM54--10576
CAV3--110580
CAPG--10638
SCIN--11105
CORO1A--11557
MAP4--12259
TMSB4XP8--12337
TWF1--14449
TMSB4XP4--18618
MAP6D1--20389
HDAC6--20439
TWF2--21814
SBDS--21855
GSN--122198
VIL1--22201
VILL--23074
FKBP4--23284
BRCA1--124158
LIMA1--24245
CDK5RAP2--124345
CCNB1--24648
TRIOBP--124727
ARAP1--25493

Network

GO:0051494

Network
Enrichment
NameDescriptionExternal IDs
MAPTmicrotubule-associated protein tau Entrez:4137  HGNC: 6893  Ensembl: ENSG00000186868  HPRD: 01142 
MAP2microtubule-associated protein 2 Entrez:4133  HPRD: 01140  HGNC: 6839  Ensembl: ENSG00000078018 
STMN2stathmin-like 2 Entrez:11075  HGNC: 10577  HPRD: 09003  Ensembl: ENSG00000104435 
MAPRE1microtubule-associated protein, RP/EB family, member 1 Entrez:22919  HGNC: 6890  HPRD: 04379  Ensembl: ENSG00000101367 
MAP1Bmicrotubule-associated protein 1B Entrez:4131  HPRD: 01139  HGNC: 6836  Ensembl: ENSG00000131711 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MAPTmicrotubule-associated protein tau
MAP2microtubule-associated protein 2
STMN2stathmin-like 2
MAPRE1microtubule-associated protein, RP/EB family, member 1
MAP1Bmicrotubule-associated protein 1B
Query geneGeneGene descriptionEdge score
MAPTMAPTmicrotubule-associated protein tau
MAP2MAP2microtubule-associated protein 2
STMN2STMN2stathmin-like 2
MAPRE1MAPRE1microtubule-associated protein, RP/EB family, member 1
MAP1BMAP1Bmicrotubule-associated protein 1B

Troyanskaya Laboratory - Princeton University