ASD

GO:0042493 response to drug (340)

GeneInput weightStandardRank
GNAO1--3
HTR2C0.25146
GAD20.25150
HTR2A0.25151
GRIN2A0.25156
ERBB40.25164
SLC1A2--71
GAD10.25190
SLC12A5--103
NEUROD1--1136
ABCC8--1161
SFRP1--204
YWHAZ0.251282
MAP1B--300
SNCA--1401
ADCY10.251466
APC0.251528
PCSK1--604
JUN--647
DRD10.251662
LRP20.251745
BDNF0.251754
KCNK3--792
ACACA--829
VLDLR0.251837
SST--869
NOS10.251908
CHRNA3--910
ATP1A3--918
ERBB3--921
ADRA1A--937
GABRG30.251990
CREB1--991
PRL0.251992
TOP1--995
PDE4A--1000
JUNB--1044
XPO1--1054
PIK3R10.2511065
ADCYAP1R1--1132
ENO2--1239
PAPD7--1250
EP300--11256
TSPO0.2511277
FYN--1284
SLC8A1--1339
RELA--1352
NME2--1434
TGFA--1563
ABCA2--1573
CA4--11617
ALDOB--1669
EMX1--1823
PARK7--11831
FOS--1839
ABCA3--1841
DUSP6--1889
CYP2C9--1931
TRPA1--1981
SCN11A--1987
DRD20.2512071
BCHE--2123
DPYSL2--2131
WFDC1--2183
CYP2A6--12218
MSH2--12299
CYP2C8--2351
GNAS--12352
POR0.2512359
LHCGR0.2512362
SLC17A3--2381
CFTR--12414
ABCB10.2512476
STAT3--12598
SREBF2--2664
LCT--2668
UBE2B--2708
DRD30.2512757
BCL20.2512759
RPS6KB1--2773
SLC6A11--2809
SMAD1--2829
PDE3A--3024
LPL--13032
SPECC1L--3048
HCN2--3076
CYP17A10.2513171
SRP19--3173
NKX6-1--3174
PTGS20.2513176
PTK2B--3191
MAS1--3300
CYP19A10.2513314
SLC6A40.2513328
SOD1--13330
CYBA--13439
CYP2C19--3471
PTPRM--3512
ABCC6--13521
TERF1--3607
MET1.013618
LGALS1--3679
SRD5A10.2513730
FABP30.2513742
NGF0.2513749
SFRP2--3758
OXCT1--3898
GIP--3965
MFSD10--3986
OTC--13989
MAT2A--3995
VAV3--4024
ATP1A10.2514084
CYP7B1--14105
CYP2B6--4125
ADD3--4376
ITGB1--4390
DVL3--4438
OXTR0.514494
SRP72--4516
CYP11A10.2514559
IL6--14578
NR1I2--4579
GRK5--4585
CDKN1A--4620
SERPINA7--4628
PDGFA--4678
CST3--14680
IL4--4723
SLC15A2--4806
ATP4A--4829
ADIPOQ0.2514834
ABAT0.2514838
SLC1A30.2515029
CYP1A10.2515095
FOSL1--5100
MAOB0.2515190
VEGFC--5203
ABCG2--5218
DDC0.2515222
HTR2B--5233
RAB6C--5239
IFNG--15255
SLC6A30.2515276
CCND1--15288
LYN--5289
CPB2--5431
CYP1A2--5437
NME1--15563
HTR1B0.2515751
TCF3--5880
PDZK1--5929
NPPB--5967
SEMA3C--6197
IL1B--16220
CTNNB10.2516229
HMGCS1--6431
TH0.2516482
REN--16631
TGIF1--16785
KCNJ11--16868
B2M--7118
ARG2--7159
RPH3AL--7341
CSAG2--7377
SLC18A2--7407
NPPC--7442
ANXA1--7465
EBP--7482
LIPE--7786
PGF--7841
IL10--17883
APOBEC1--8376
CYP3A4--8506
CHAT--8747
ACTC1--18770
DAD1--8854
NFATC2--8993
AACS--9069
EDN1--9566
ADORA2A0.2519605
GAL--9612
SLC9A1--9719
TGFBR2--19756
RHOC--9929
COMT0.2519945
SOCS1--9996
ATG5--10016
ABCD3--10047
NAT8--10054
AMH--10166
BDKRB2--10260
MAP2K6--10398
CD69--10540
MMP7--10585
HMGCS2--10713
HSD11B2--10731
FAS--110857
GNA12--10962
INPPL1--11037
SMTNL1--11045
ADAM17--11074
GATA4--111137
SLC22A1--11144
SLC19A10.25111151
PEBP1--11226
AIM2--11236
NES--11295
ABCG5--11513
APOC2--11692
UTS2R--11874
BAG1--11884
SOD2--12001
ACADM--12060
MVD--12082
HNF4A--112281
PDGFB--12484
NOS3--12710
GRK1--112718
APOA2--12739
IGFBP2--12744
CSAG3--12830
SLC22A12--12877
DDIT3--12944
CPS1--112985
GK--13016
TNFRSF11B--13020
REST--13067
MVP--13161
USP47--13183
BLMH--13327
GATA6--113349
LTA--13444
GGH--13518
BLOC1S3--13724
ABCC1--13942
ICAM1--14063
ARG1--114097
TXNIP--14451
PMS2--14609
TGFB10.25114736
TIMP4--14828
BAK1--15240
LOX--15392
QDPR0.25115452
TBXA2R--15453
SOCS3--15768
ALDH1A3--15783
DNMT3B--16091
CASP12--16225
RPP21--16384
SREBF1--16874
CD380.25117453
AQP7P3--18146
UQCRFS1P1--18735
ND1--19541
HDAC3--19605
TNF0.25119823
MGST1--20154
ABCB4--120189
TLR3--20315
XBP1--20701
AQP1--21019
SRR--21028
MYC--121066
SS18--21353
AQP7--21492
CCL5--21529
ERBB2--121638
IKBKB--21674
NBN--121778
NCF2--121812
NDUFA10--121843
SRP14--21871
CAPN3--121898
BGLAP--21911
PPARG--121945
TP530.25121968
PEMT--21989
THBS1--21993
UGT1A1--122048
CARD9--122070
FZD1--22086
CALR--22356
ALDH3A10.25122463
PMS2CL--22581
COQ7--22662
XRCC1--22854
XPC--123003
TYMS--23100
UQCRFS1--23150
CDK4--23190
BCAR3--23354
SRP54--23370
ACSL1--23377
IGF20.25123391
CROT--23397
SLC22A5--123416
NCKAP1L--23440
CDH1--123441
TXN2--23468
ASS1--123526
LTC4S--23557
PPOX--123575
BDH1--23717
MMP9--23766
CCNE1--23811
PRSS8--23819
EI24--23846
SLC22A18--123875
CDK1--24001
NNMT--24009
SRP68--24026
SMPD1--124037
TOP2A--24163
GNPAT--124183
GPX3--24352
GCLM--24501
HADHA--24509
CPT1A--24551
PARP4--24640
CCNB1--24648
CAV1--124767
IL1RN0.25124819
NME1-NME2--24831
PLIN2--24897
ENO3--24960
LCK--24966
MGMT--25043
PNP--125122
PAM--25208
RAD54B--25212
LCN2--25216
HADH--125281
FXN--125366
COL18A1--25381
MLH1--125572
RAD54L--125583
CENPF--25617
CTPS1--25776

Network

GO:0042493

Network
Enrichment
NameDescriptionExternal IDs
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O Entrez:2775  HPRD: 00757  HGNC: 4389  Ensembl: ENSG00000087258 
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Entrez:3358  HGNC: 5295  HPRD: 02429  Ensembl: ENSG00000147246 
GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) Entrez:2572  HPRD: 11817  HGNC: 4093  Ensembl: ENSG00000136750 
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Entrez:3356  HPRD: 01638  Ensembl: ENSG00000102468  HGNC: 5293 
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
Query geneGeneGene descriptionEdge score
GNAO1GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
HTR2CHTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
GAD2GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
HTR2AHTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A

Troyanskaya Laboratory - Princeton University