ASD

GO:0003001 generation of a signal involved in cell-cell signaling (116)

GeneInput weightStandardRank
SYT1--5
SNAP250.2516
SYN2--7
NTRK20.25128
SLC17A7--35
GAD20.25150
VAMP2--57
GAD10.25190
PCLO--114
NEUROD1--1136
SYNJ1--178
MEG3--201
CACNA1A--1231
SLC6A10.251238
NLGN10.251265
RIMS2--273
YWHAZ0.251282
CACNA1B--319
STX1A0.251449
RAB3A0.251520
RIMS1--622
RAPGEF40.251635
STXBP1--659
RAB14--679
SYN10.251684
LRP20.251745
BDNF0.251754
CAMK2G--925
CPLX20.251956
GLS2--1148
CARTPT0.2511181
HRH3--1240
VGF0.2511243
SNPH--1251
SYN3--1286
SPTBN2--11344
BAIAP3--1417
GRM2--1421
SYT4--1501
UNC13A--1521
EDN3--11522
DOC2A0.2511649
FZD4--11666
FKBP1B--1700
PPFIA3--1813
SEPT5--1818
SLC32A1--1821
GLS--1895
CGA0.2511927
GHSR0.2512085
SLC6A12--2221
SLC5A7--2681
SLC6A11--2809
CPLX1--2921
SLC6A13--3069
ACVR2B--13179
OTOF--13204
MC4R0.2513280
SLC22A2--3305
TBX3--3843
CPLX3--3906
VAMP1--4135
SLC38A2--4294
GHRH--4568
IL6--14578
ABAT0.2514838
BRSK1--4979
HNF1A--15114
DDC0.2515222
LYN--5289
DNAJC5--5428
SLC18A3--5430
GRM4--5804
SLC30A8--15810
SYT2--5886
HSPA8--5945
WNT7A--6375
TH0.2516482
SMAD2--7224
SLC18A2--7407
ANXA1--7465
CCKAR--7616
PDX1--18378
CHAT--8747
TRPV10.2518765
ALDH5A1--9013
DOC2B--9220
GHRL0.2519333
HNF1B--19562
EDN1--9566
GAL--9612
INHBA--9731
FAM3B--9848
FFAR4--10349
PPT1--110364
ADM--10761
UNC13B--12427
GPR119--13231
MAOA0.25113422
STX4--13426
CYB5R4--14019
MAFA--14795
GIPC1--15140
DGAT1--15809
EXOC3L1--16762
DVL1P1--19166
PSEN1--20241
EIF2AK3--20407
P2RX1--20551
XBP1--20701
DVL1--21155
SNAPIN--22880
BLOC1S6--23642
SYK--23795
IL1RN0.25124819
LTBP4--25140

Network

GO:0003001

Network
Enrichment
NameDescriptionExternal IDs
SYT1synaptotagmin I Entrez:6857  HPRD: 01710  HGNC: 11509  Ensembl: ENSG00000067715 
SNAP25synaptosomal-associated protein, 25kDa Entrez:6616  Ensembl: ENSG00000132639  HPRD: 02637  HGNC: 11132 
SYN2synapsin II Entrez:6854  HPRD: 02857  HGNC: 11495 
NTRK2neurotrophic tyrosine kinase, receptor, type 2 Entrez:4915  Ensembl: ENSG00000148053  HPRD: 02712  HGNC: 8032 
SLC17A7solute carrier family 17 (vesicular glutamate transporter), member 7 Entrez:57030  HGNC: 16704  Ensembl: ENSG00000104888  HPRD: 05551 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SYT1synaptotagmin I
SNAP25synaptosomal-associated protein, 25kDa
SYN2synapsin II
NTRK2neurotrophic tyrosine kinase, receptor, type 2
SLC17A7solute carrier family 17 (vesicular glutamate transporter), member 7
Query geneGeneGene descriptionEdge score
SYT1SYT1synaptotagmin I
SNAP25SNAP25synaptosomal-associated protein, 25kDa
SYN2SYN2synapsin II
NTRK2NTRK2neurotrophic tyrosine kinase, receptor, type 2
SLC17A7SLC17A7solute carrier family 17 (vesicular glutamate transporter), member 7

Troyanskaya Laboratory - Princeton University