ASD

GO:0021983 pituitary gland development (36)

GeneInput weightStandardRank
SOX2--1125
PAX60.251355
SALL1--408
PCSK1--604
POU3F2--653
CREB1--991
ISL1--1441
NR0B1--11715
SOX3--2042
BMPR1A--2059
DRD20.2512071
GHRHR--2312
NKX2-1--2488
GATA2--12710
WNT5A--2870
GSX1--2967
ALDH1A2--3466
SRD5A10.2513730
FGF10--14373
OTP--4497
GHRH--4568
BMP4--15180
ETS1--5230
SLC6A30.2515276
HES10.2515662
GLI2--15731
SMO0.2515864
NOG--17650
FGF2--9627
DUOX2--19797
TBX19--14813
ALDH1A3--15783
KDM1A--15967
WNT4--21840
PITX10.25123078
CDH1--123441

Network

GO:0021983

Network
Enrichment
NameDescriptionExternal IDs
SOX2SRY (sex determining region Y)-box 2 Entrez:6657  HGNC: 11195  HPRD: 08921  Ensembl: ENSG00000181449 
PAX6paired box 6 Entrez:5080  HPRD: 06167  Ensembl: ENSG00000007372  HGNC: 8620 
SALL1sal-like 1 (Drosophila) Entrez:6299  HGNC: 10524  Ensembl: ENSG00000103449  HPRD: 03742 
PCSK1proprotein convertase subtilisin/kexin type 1 Entrez:5122  HGNC: 8743  HPRD: 01201  Ensembl: ENSG00000175426 
POU3F2POU class 3 homeobox 2 Entrez:5454  HPRD: 02734  Ensembl: ENSG00000184486  HGNC: 9215 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX2SRY (sex determining region Y)-box 2
PAX6paired box 6
SALL1sal-like 1 (Drosophila)
PCSK1proprotein convertase subtilisin/kexin type 1
POU3F2POU class 3 homeobox 2
Query geneGeneGene descriptionEdge score
SOX2SOX2SRY (sex determining region Y)-box 2
PAX6PAX6paired box 6
SALL1SALL1sal-like 1 (Drosophila)
PCSK1PCSK1proprotein convertase subtilisin/kexin type 1
POU3F2POU3F2POU class 3 homeobox 2

Troyanskaya Laboratory - Princeton University