ASD

GO:0000398 nuclear mRNA splicing, via spliceosome (193)

GeneInput weightStandardRank
NOVA1--18
TRA2B--65
SRSF2--218
SNRPD3--256
RALY--295
SNRPE--316
POLR2E--322
SRSF3--383
SRPK2--412
DDX5--506
HNRNPUL1--541
PTBP1--583
CELF3--607
LSM3--715
SNRPG--716
SNRPB--742
HNRNPK--746
HNRNPR--769
SRSF9--797
HNRNPU--825
HNRNPH3--872
PABPN1--1878
POLR2B--946
MBNL1--1113
SYNCRIP--1150
PSIP1--1165
PAPOLA--1246
CELF2--1278
HNRNPA2B1--1293
SRSF1--1307
PCBP1--1519
HNRNPA3--1524
RBM5--1665
DDX1--1667
PNN--1717
PTBP2--1750
POLR2A--1753
MAGOH--1773
SRSF5--1815
LSM7--1840
SNRPF--1918
SF3A2--1973
CELF4--1983
SFPQ--1988
SFSWAP--2035
HNRNPC--2060
CPSF1--2095
HNRNPD--2162
RBM8A--12178
POLR2K--2246
SRSF10--2264
SRSF11--2295
RBMX--2432
SNRPA--2524
SRSF12--2655
CDK13--2792
GTF2F1--2800
HNRNPA1--3011
POLR2J--3085
PRPF4B--3124
POLR2L--3236
HNRNPH2--3246
SRRM1--3399
LSM2--3451
RNPS1--3493
SNRPA1--3495
POLR2G--3505
DDX39A--3534
SF3B1--3552
SRSF7--3630
SNRPD2--3779
SNRPB2--3794
YTHDC1--4002
CACTIN--4013
HNRNPM--4185
PCF11--4196
SRSF4--4276
PRPF6--4396
SF1--4401
DDX41--4418
DNAJC8--4441
FUS--14451
SNRNP200--14522
CPSF7--4605
SCAF11--4749
SF3B4--4751
DDX39B--4777
SNRNP70--4833
WBP4--4950
HNRNPA0--5084
SNRPC--5166
TRA2A--5772
CDC5L--5877
PPIH--6173
CRNKL1--6202
SF3B2--6401
SRRM2--6851
SNW1--6943
FRG1--7023
GEMIN8--7155
DHX38--7373
DHX9--7424
CELF1--7554
RBM22--7828
PRPF8--18079
DDX23--8085
EIF4A3--8281
XAB2--9495
HNRNPH1--9630
SF3A1--9726
SUGP1--9744
CDC40--9899
PRPF31--110092
SRSF6--10440
PRPF3--110629
PCBP2--11316
AQR--11476
ZCCHC8--11507
SF3B5--11641
POLR2F--11818
SMC1A--12199
TXNL4A--12368
DGCR14--12563
POLR2I--12952
U2AF1--12962
SNRPD1--13025
ISY1--13471
CD2BP2--13643
YBX1--13938
PABPC1--13951
CCAR1--14316
PPWD1--14395
POLR2C--15047
DHX8--15274
NHP2L1--16285
SART1--16322
HNRNPL--16396
WDR83--17259
U2AF2--17548
GEMIN7--18122
NAA38--20047
POLR2H--20441
CLNS1A--20532
ALYREF--20561
EFTUD2--20972
UPF3B--21134
CSTF3--21286
PLRG1--21678
PRPF19--21797
TFIP11--22076
SLU7--22275
PHAX--22474
GPATCH1--22550
SF3B3--22604
SMN1--122636
PRMT7--22721
PHF5A--22733
GTF2F2--22776
SNRNP40--22792
CWC15--22832
CWC22--22842
HNRNPF--22937
DHX35--23125
SF3A3--23183
ZRSR2--23662
CWC27--23681
PPIL3--23707
NCBP2--23844
NUDT21--23994
CSTF1--24092
SMN2--124136
PRPF4--24171
CLP1--24215
CPSF3--24277
SNUPN--24295
USP39--24296
RSRC1--24299
GEMIN6--24348
CPSF2--24525
SYF2--24547
TGS1--24613
PPIE--24778
PPIL1--25036
GEMIN2--25084
DDX20--25360
POLR2D--25367
GEMIN5--25589
SKIV2L2--25596
PRMT5--25630
NCBP1--25632
GEMIN4--25666
CSTF2--25781
WDR77--25811

Network

GO:0000398

Network
Enrichment
NameDescriptionExternal IDs
NOVA1neuro-oncological ventral antigen 1 Entrez:4857  HPRD: 03693  Ensembl: ENSG00000139910  HGNC: 7886 
TRA2Btransformer 2 beta homolog (Drosophila) Entrez:6434  HGNC: 10781  HPRD: 04097 
SRSF2serine/arginine-rich splicing factor 2 Entrez:6427  HPRD: 02888  HGNC: 10783  Ensembl: ENSG00000161547 
SNRPD3small nuclear ribonucleoprotein D3 polypeptide 18kDa Entrez:6634  HGNC: 11160  HPRD: 03039 
RALYRALY heterogeneous nuclear ribonucleoprotein Entrez:22913  HGNC: 15921  HPRD: 11480  Ensembl: ENSG00000125970 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NOVA1neuro-oncological ventral antigen 1
TRA2Btransformer 2 beta homolog (Drosophila)
SRSF2serine/arginine-rich splicing factor 2
SNRPD3small nuclear ribonucleoprotein D3 polypeptide 18kDa
RALYRALY heterogeneous nuclear ribonucleoprotein
Query geneGeneGene descriptionEdge score
NOVA1NOVA1neuro-oncological ventral antigen 1
TRA2BTRA2Btransformer 2 beta homolog (Drosophila)
SRSF2SRSF2serine/arginine-rich splicing factor 2
SNRPD3SNRPD3small nuclear ribonucleoprotein D3 polypeptide 18kDa
RALYRALYRALY heterogeneous nuclear ribonucleoprotein

Troyanskaya Laboratory - Princeton University