ASD

GO:0031098 stress-activated protein kinase signaling cascade (112)

GeneInput weightStandardRank
FGF12--181
MAPK10--1194
MEF2C0.251248
RB1CC1--1279
MAPK8IP1--1326
MAP2K10.251474
MAP3K9--500
FGF14--1522
MAP2K4--579
MAP3K12--592
JUN--647
RPS6KA5--677
RPS6KA20.251711
MINK1--777
RPS6KA3--861
MAPK1--985
CREB1--991
MAP2K20.2511066
ATF2--1137
MAP3K5--1245
MAPK11--1258
ELK1--1329
SPAG9--1398
TNIK--1544
MAPK8--1764
MAP3K10--1767
FOS--1839
GAB1--1864
DUSP6--1889
PKN1--1964
GPS1--2030
MAP3K7--2169
MAPK9--2324
TAOK20.2512490
MAPK8IP3--2496
TAB2--2777
MAP3K13--2868
WNT5A--2870
SH2D3C--3315
TRIB1--3331
MAPKAPK2--3441
DAB2IP--3635
MAPKBP1--3672
AGT--13783
DUSP4--4300
MAPK7--4626
MAPK14--4729
MAP4K3--4763
MAP4K5--4887
DUSP19--5073
UBC--5781
DUSP3--5845
MEF2A--6060
MAPK30.2516096
DUSP10--6196
CRKL--6254
WNT7A--6375
TAB3--6412
TNFRSF19--6510
MAP3K4--6590
MAP3K1--16751
NPHS1--6850
DUSP7--7411
DUSP9--7653
WNT7B--7693
RBM4--8366
MAP2K7--8382
MAP2K3--9005
IRAK1--9309
DAXX--9639
TAB1--9783
RHOC--9929
MAP3K2--10013
MAP2K6--10398
GFRAL--10645
AXIN1--110905
ADORA2B--11164
IRAK2--11461
FGD4--111677
MDFI--11799
CCL19--11890
BIRC7--12220
CDC42EP5--12367
ARHGEF6--13050
RIPK2--13928
DBNL--14433
MDFIC--14627
TRAF6--14847
ATF1--15773
GPS2--20293
CCM2--20854
MAP4K2--20924
STRADB--21620
RPS6KA1--22219
UBB--22223
MAP4K1--22293
MUL1--22450
NOD2--122677
PTPLAD1--22865
RPS27A--22920
RIPK1--23173
MAP3K11--23341
IRAK4--23495
MAPKAPK3--23643
NOD1--23711
SYK--23795
IKBKG--123817
CDK1--24001
UBA52--24116
MAP3K6--24401
SH2D3A--24548
CRYAB--124949

Network

GO:0031098

Network
Enrichment
NameDescriptionExternal IDs
FGF12fibroblast growth factor 12 Entrez:2257  HGNC: 3668  HPRD: 03303 
MAPK10mitogen-activated protein kinase 10 Entrez:5602  HGNC: 6872  Ensembl: ENSG00000109339  HPRD: 04207 
MEF2Cmyocyte enhancer factor 2C Entrez:4208  HGNC: 6996  Ensembl: ENSG00000081189  HPRD: 02809 
RB1CC1RB1-inducible coiled-coil 1 Entrez:9821  HPRD: 06019  HGNC: 15574  Ensembl: ENSG00000023287 
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 1 Entrez:9479  HPRD: 05223  Ensembl: ENSG00000121653  HGNC: 6882 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
FGF12fibroblast growth factor 12
MAPK10mitogen-activated protein kinase 10
MEF2Cmyocyte enhancer factor 2C
RB1CC1RB1-inducible coiled-coil 1
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 1
Query geneGeneGene descriptionEdge score
FGF12FGF12fibroblast growth factor 12
MAPK10MAPK10mitogen-activated protein kinase 10
MEF2CMEF2Cmyocyte enhancer factor 2C
RB1CC1RB1CC1RB1-inducible coiled-coil 1
MAPK8IP1MAPK8IP1mitogen-activated protein kinase 8 interacting protein 1

Troyanskaya Laboratory - Princeton University