ASD

GO:0032272 negative regulation of protein polymerization (41)

GeneInput weightStandardRank
STMN2--221
MAPRE1--296
SNCA--1401
PFN2--431
SLIT2--582
CLIP3--739
CAPZB--953
SPTBN4--1223
DMTN--1226
TMSB10--1299
SPTBN2--11344
KANK1--1493
ADD2--1685
SPTAN1--12078
TMSB15A--2105
SPTB--2288
TMSB15B--2402
CAPZA2--2428
CAPZA1--2513
INPP5J--2851
SPTA1--14158
TMSB4X--4291
STMN1--4584
CAPZA3--5405
RDX--15514
SPTBN5--5948
TBCD--6876
SPTBN1--8272
TMSB4Y--8925
ADD1--19458
AVIL--10360
CAPG--10638
SCIN--11105
TMSB4XP8--12337
TWF1--14449
TMSB4XP4--18618
TWF2--21814
GSN--122198
VIL1--22201
VILL--23074
TRIOBP--124727

Network

GO:0032272

Network
Enrichment
NameDescriptionExternal IDs
STMN2stathmin-like 2 Entrez:11075  HGNC: 10577  HPRD: 09003  Ensembl: ENSG00000104435 
MAPRE1microtubule-associated protein, RP/EB family, member 1 Entrez:22919  HGNC: 6890  HPRD: 04379  Ensembl: ENSG00000101367 
SNCAsynuclein, alpha (non A4 component of amyloid precursor) Entrez:6622  HPRD: 01227  HGNC: 11138  Ensembl: ENSG00000145335 
PFN2profilin 2 Entrez:5217  Ensembl: ENSG00000070087  HGNC: 8882  HPRD: 01451 
SLIT2slit homolog 2 (Drosophila) Entrez:9353  Ensembl: ENSG00000145147  HPRD: 04776  HGNC: 11086 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
STMN2stathmin-like 2
MAPRE1microtubule-associated protein, RP/EB family, member 1
SNCAsynuclein, alpha (non A4 component of amyloid precursor)
PFN2profilin 2
SLIT2slit homolog 2 (Drosophila)
Query geneGeneGene descriptionEdge score
STMN2STMN2stathmin-like 2
MAPRE1MAPRE1microtubule-associated protein, RP/EB family, member 1
SNCASNCAsynuclein, alpha (non A4 component of amyloid precursor)
PFN2PFN2profilin 2
SLIT2SLIT2slit homolog 2 (Drosophila)

Troyanskaya Laboratory - Princeton University