ASD

GO:0009880 embryonic pattern specification (49)

GeneInput weightStandardRank
SATB20.251108
FGFR2--1165
PCSK6--731
LRP6--778
PGAP1--865
MEOX2--949
BMP7--987
PTCH1--11149
CXXC4--1472
SMAD3--1541
CITED1--1867
LHX1--1926
SMAD6--2079
DLL1--2143
NODAL--12184
T--2584
SMAD1--2829
SIM2--2848
WNT5A--2870
SMAD4--2927
WNT1--3263
EPB41L5--3311
HOXB6--3623
TBX3--3843
FGF10--14373
IHH--14742
WNT3--4799
WNT3A--4844
C2CD3--5468
EFNB1--16175
CTNNB10.2516229
WNT7A--6375
TDRD5--6427
HOXD8--6575
TDGF1--6833
RIPPLY2--7060
SMAD2--7224
RIPPLY1--8488
GDF3--19473
SMAD5--11520
OOEP--12066
FRS2--12610
MEOX1--13570
TCF7L1--13850
NOTO--14851
RPGRIP1L--19545
FZD5--21891
PLD6--22708
DISP1--23291

Network

GO:0009880

Network
Enrichment
NameDescriptionExternal IDs
SATB2SATB homeobox 2 Entrez:23314  Ensembl: ENSG00000119042  HPRD: 12178  HGNC: 21637 
FGFR2fibroblast growth factor receptor 2 Entrez:2263  HPRD: 01492  Ensembl: ENSG00000066468  HGNC: 3689 
PCSK6proprotein convertase subtilisin/kexin type 6 Entrez:5046  HPRD: 01329  HGNC: 8569  Ensembl: ENSG00000140479 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
PGAP1post-GPI attachment to proteins 1 Entrez:80055  HGNC: 25712  HPRD: 10147 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SATB2SATB homeobox 2
FGFR2fibroblast growth factor receptor 2
PCSK6proprotein convertase subtilisin/kexin type 6
LRP6low density lipoprotein receptor-related protein 6
PGAP1post-GPI attachment to proteins 1
Query geneGeneGene descriptionEdge score
SATB2SATB2SATB homeobox 2
FGFR2FGFR2fibroblast growth factor receptor 2
PCSK6PCSK6proprotein convertase subtilisin/kexin type 6
LRP6LRP6low density lipoprotein receptor-related protein 6
PGAP1PGAP1post-GPI attachment to proteins 1

Troyanskaya Laboratory - Princeton University