ASD

GO:0000209 protein polyubiquitination (156)

GeneInput weightStandardRank
PSMA1--42
PSMB3--79
PSMA4--95
PSMD14--120
PSMD8--144
PSMA5--219
PSMB1--318
PSMA3--373
PSMC4--380
PSMC6--405
PSMB7--554
PSMB4--562
UBE2E3--574
PSMD2--595
UBE2D2--600
TTC3--627
PARK20.251634
UBE2D3--661
UBE2N--693
PSMB6--696
UBE2S--748
PSMA7--782
PSMC3--794
PSMC5--831
PSMD1--867
PSMD6--884
PSMC1--904
PSMD3--909
UBE3A0.251917
PSMD11--943
PSMC2--952
PSMD13--994
RNF4--1036
PSMD4--1166
UBE2V2--1207
UBE2A0.2511473
PSMA6--1492
UBR5--1553
RNF41--1566
PSME4--1576
FBXW11--1610
PSMA2--1693
NPEPPS--1838
CDC34--1858
TNKS--1911
PSMD10--2012
PSMD12--2120
UBE2G1--2263
ZFP91--2271
PSMD7--2386
DZIP3--2398
BTRC--2430
UBE2B--2708
UBE2L3--2735
UBE2K--2746
BCL20.2512759
UBE4B--2923
UBE2R2--2944
STUB1--3156
TNFAIP3--3628
RNF152--3891
FZR1--3987
BARD1--14151
RNF6--14587
SMURF1--4696
HUWE1--4890
MARCH6--4985
UBC--5781
RNF5--5935
UBE2E1--6513
UBE2G2--6750
MAP3K1--16751
ZSWIM2--7154
MARCH1--7173
ARIH2--7215
UBE3C--7312
PSME2--7488
UBE2W--7579
PSMB9--7654
PSMB2--7801
PSMA8--8114
UBE2Q2--8469
ANAPC2--8902
CDC23--9012
TNKS2--9062
CDKN2A--19650
ITCH--10863
ANAPC10--11143
RNF168--11188
UBE4A--11244
PSME1--11612
WWP2--12103
TRIM320.25112319
PSMB8--12378
UBE2V1--12516
ANAPC13--12521
TPP2--12568
LRSAM1--12996
BLMH--13327
ANAPC11--13665
PSMD9--13761
BIRC2--13848
PSMB11--14440
PSMB10--14502
MARCH5--14597
UBOX5--14743
TRAF6--14847
RNF167--14890
CDC27--14913
UBE2E2--15070
UBE2H0.25115142
RNF187--15734
NHLRC1--115939
PSME3--17451
PSMD5--18391
FBXO4--19716
AMFR--19835
ZNF738--20343
HDAC6--20439
PPIL2--20621
RNF146--20728
CDC26--21067
ERCC8--121190
RNF31--21239
NEDD40.25121604
PRPF19--21797
TRIM56--22057
UBB--22223
CHFR--22695
RPS27A--22920
RNF20--22923
PSMF1--22952
RNF216--23131
RBCK1--23437
MARCH8--23556
TRAF2--23633
LNPEP--23644
UBE2D1--23789
UBE2D4--23886
SHARPIN--23940
UBA52--24116
BRCA1--124158
FBXO22--24394
TRIM21--24431
G2E3--24435
PSMB5--24489
DDB2--124762
UBE2T--24873
ANAPC7--24876
ANAPC5--24931
DTL--25201
ANAPC4--25215
UBE2C--25279
CDC16--25415
SKP2--25453
ANAPC1--25548

Network

GO:0000209

Network
Enrichment
NameDescriptionExternal IDs
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1 Entrez:5682  Ensembl: ENSG00000129084  HPRD: 04170  HGNC: 9530 
PSMB3proteasome (prosome, macropain) subunit, beta type, 3 Entrez:5691  HPRD: 03709  Ensembl: ENSG00000108294  HGNC: 9540 
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4 Entrez:5685  Ensembl: ENSG00000041357  HPRD: 10168  HGNC: 9533 
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 Entrez:10213  HGNC: 16889  Ensembl: ENSG00000115233  HPRD: 06208 
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 Entrez:5714  Ensembl: ENSG00000099341  HPRD: 10171  HGNC: 9566 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMB3proteasome (prosome, macropain) subunit, beta type, 3
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
Query geneGeneGene descriptionEdge score
PSMA1PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMB3PSMB3proteasome (prosome, macropain) subunit, beta type, 3
PSMA4PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
PSMD14PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD8PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8

Troyanskaya Laboratory - Princeton University