ASD

GO:0014070 response to organic cyclic compound (216)

GeneInput weightStandardRank
GNAO1--3
CNR10.25110
GRIN2A0.25156
PRKCE--156
GRIN1--167
SFRP1--204
SLC6A10.251238
GABBR10.251352
DRD50.251482
TAC10.251543
GRIN2B1.01599
PCSK1--604
JUN--647
DRD10.251662
CCND2--689
ACACA--829
GNAL--860
RYR2--1862
CHRNA3--910
PRL0.251992
WNT10B--1030
JUNB--1044
CDKN1B--1067
ENO2--1239
EP300--11256
STC1--1273
PPP2R2A--1304
RELA--1352
NEDD8--1368
KCNK1--1496
CHRNA40.2511580
BAD--1647
CHRNA70.511657
ALDOB--1669
GUCY1A3--1730
LEF1--1731
FOS--1839
DUSP6--1889
RXRG0.2511916
STS0.2512045
DRD20.2512071
DPYSL2--2131
TRH--2296
MSH2--12299
GSK3A--2346
BTRC--2430
NFIA--2434
HSP90AB1--2440
PEA15--2463
TAC3--2507
TACR3--2526
STAT3--12598
DRD30.2512757
BCL20.2512759
RPS6KB1--2773
SMAD1--2829
WNT5A--2870
GNAT3--2884
SPECC1L--3048
FOXF1--13053
CDK50.2513113
CYP17A10.2513171
NKX6-1--3174
PTGS20.2513176
PTK2B--3191
EDNRA--13271
CYP19A10.2513314
ALDOC--3334
CYBA--13439
BTG2--3504
F7--3543
MET1.013618
LGALS1--3679
CHRNB4--3723
SRD5A10.2513730
NGF0.2513749
CD83--3832
PRKAA2--3958
GIP--3965
SLC22A8--3982
ACSL3--4184
SMAD9--14245
FGF10--14373
OXTR0.514494
IL1A--4552
CYP11A10.2514559
IL6--14578
CDKN1A--4620
CST3--14680
IL4--4723
SLC7A11--4816
ABAT0.2514838
ADRBK1--4864
DBH0.2514946
PKLR--5039
CYP1A10.2515095
FOSL1--5100
RAE1--5165
BMP4--15180
SLC6A30.2515276
CCND1--15288
LYN--5289
TAT--15696
HTR1B0.2515751
SHC1--5839
AXIN2--15927
PLCG1--5952
ADRA1B0.2515964
NPPB--5967
TGFBR1--16027
IL1B--16220
CTNNB10.2516229
HMGCS1--6431
AANAT0.2516439
TH0.2516482
SLC22A6--6911
DRD40.2517058
BCL2L1--7198
ANGPT2--7366
SLC18A2--7407
ANXA1--7465
TACR1--7688
HSD17B30.2517714
IL13--7741
PSMB2--7801
ALPL--18001
AACS--9069
EDN1--9566
ATP12A--9584
ADORA2A0.2519605
ASNS--9679
SLC9A1--9719
MMP14--9775
SDC20.2519905
COMT0.2519945
OXT0.25110022
GHR--110058
AMH--10166
SELP--10263
HMGCS2--10713
AXIN1--110905
PEBP1--11226
CEBPA--111468
AHR--11579
AVP--111615
FADS1--11633
CTNNA1--11705
CHRNA5--11781
BAG1--11884
CCL19--11890
PDGFB--12484
NOS3--12710
HNMT--13018
ICAM1--14063
RYR1--114071
FNTB--14202
PRKCQ--14566
TGFB10.25114736
RXRA0.25115046
BAK1--15240
CDKN2B--15696
SOCS3--15768
ATF1--15773
CASP12--16225
OCLN--116255
PLA2G4F--17178
ND1--19541
CHRNB1--19654
TNF0.25119823
CHRNB20.25120277
HMOX1--20520
TIMP3--20931
ITGA6--21003
SRR--21028
CHRFAM7A--21295
FDX1--21406
CHURC1--21511
CCL5--21529
TAF9B--21603
TAF2--21614
NCF2--121812
BGLAP--21911
CTGF--21927
PPARG--121945
UGT1A1--122048
ALDH3A10.25122463
PLD2--23098
CDA--23240
ACSL1--23377
IGF20.25123391
TXN2--23468
CTSV--23615
MMP9--23766
CCNE1--23811
CDK1--24001
SMPD1--124037
LUM--24067
P2RY2--24073
SERPINA1--124081
ADA0.5124175
EPHX1--124205
GPX3--24352
LONP2--24432
CPT1A--24551
CAD--24579
CTSB--24596
CCNB1--24648
IL1RN0.25124819
UROD--124886
PLIN2--24897
MGMT--25043
FXN--125366
MLH1--125572
ACAT1--125660
DHFR0.25125735
CHEK1--25817

Network

GO:0014070

Network
Enrichment
NameDescriptionExternal IDs
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O Entrez:2775  HPRD: 00757  HGNC: 4389  Ensembl: ENSG00000087258 
CNR1cannabinoid receptor 1 (brain) Entrez:1268  HGNC: 2159  Ensembl: ENSG00000118432  HPRD: 00259 
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
PRKCEprotein kinase C, epsilon Entrez:5581  HPRD: 01500  HGNC: 9401  Ensembl: ENSG00000171132 
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1 Entrez:2902  HGNC: 4584  HPRD: 15926  Ensembl: ENSG00000176884 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
CNR1cannabinoid receptor 1 (brain)
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
PRKCEprotein kinase C, epsilon
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1
Query geneGeneGene descriptionEdge score
GNAO1GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
CNR1CNR1cannabinoid receptor 1 (brain)
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
PRKCEPRKCEprotein kinase C, epsilon
GRIN1GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1

Troyanskaya Laboratory - Princeton University