ASD

GO:0030177 positive regulation of Wnt receptor signaling pathway (54)

GeneInput weightStandardRank
FGFR2--1165
SFRP1--204
FGF9--241
SALL1--408
SOX4--581
EDA--1615
DISC10.251723
LRP6--778
CSNK1D--811
WNT10B--1030
WNT2B--1126
CSNK1E0.2511225
SMAD3--1541
UBR5--1553
FGFR3--11648
WNT20.2511783
TNKS--1911
MACF1--1938
DKK2--2075
DLX5--2361
ILK--2917
USP34--2985
RSPO2--3476
SFRP4--3511
SFRP2--3758
SKI--4231
FGF10--14373
DIXDC1--4469
ZEB2--4607
WNT3A--4844
MBD2--4876
PPM1A--5058
GPC3--15153
RSPO1--5850
WNT7A--6375
BAMBI--7548
CAPRIN2--8066
ZRANB1--8282
TNKS2--9062
HHEX--12438
JUP--112627
TLR2--112838
NRARP--15165
SHH--115942
WLS--16366
NFKB1--20216
RNF146--20728
DVL1--21155
WNT4--21840
TRPM4--21966
YAP1--22816
COL1A1--124560
CAV1--124767
DAB2--24837

Network

GO:0030177

Network
Enrichment
NameDescriptionExternal IDs
FGFR2fibroblast growth factor receptor 2 Entrez:2263  HPRD: 01492  Ensembl: ENSG00000066468  HGNC: 3689 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
FGF9fibroblast growth factor 9 Entrez:2254  HPRD: 02951  HGNC: 3687  Ensembl: ENSG00000102678 
SALL1sal-like 1 (Drosophila) Entrez:6299  HGNC: 10524  Ensembl: ENSG00000103449  HPRD: 03742 
SOX4SRY (sex determining region Y)-box 4 Entrez:6659  HPRD: 01695  HGNC: 11200  Ensembl: ENSG00000124766 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
FGFR2fibroblast growth factor receptor 2
SFRP1secreted frizzled-related protein 1
FGF9fibroblast growth factor 9
SALL1sal-like 1 (Drosophila)
SOX4SRY (sex determining region Y)-box 4
Query geneGeneGene descriptionEdge score
FGFR2FGFR2fibroblast growth factor receptor 2
SFRP1SFRP1secreted frizzled-related protein 1
FGF9FGF9fibroblast growth factor 9
SALL1SALL1sal-like 1 (Drosophila)
SOX4SOX4SRY (sex determining region Y)-box 4

Troyanskaya Laboratory - Princeton University