ASD

GO:0008286 insulin receptor signaling pathway (138)

GeneInput weightStandardRank
YWHAB0.25145
ATP6V0B--84
KRAS--1143
FGFR2--1165
FGF9--241
ATP6V1G2--247
ATP6V0D1--258
AKT10.251303
SHC3--330
ATP6V0C0.251350
MAP2K10.251474
IGF1R--631
ATP6V1A--981
MAPK1--985
FGF1--1005
IRS1--11052
PIK3R10.2511065
MAP2K20.2511066
CAB39--1116
ATP6V1F--1557
ATP6V1B2--1583
IRS2--11607
FGF5--1645
FGFR3--11648
PIK3R3--1659
BAIAP20.2511725
ATP6V0A1--1748
TSC10.2511844
GAB1--1864
FGF7--1995
GRB10--2023
EIF4E0.2512043
SHC2--2147
AP3S1--2254
GSK3A--2346
FGFR1--2550
EIF4G1--2657
GRB2--2662
RPS6KB1--2773
PIK3CA0.2512782
FGF23--12939
FOXO3--2950
AKT2--13025
PDE3B--3088
SOS1--13181
FGF3--3192
ATP6V1E1--3217
SMARCC1--3276
FGF20--3325
KL--3641
RHEB--3911
PRKAA2--3958
IGFBP1--4094
PDPK1--4150
SOCS7--4328
FGF10--14373
CRK--4478
FGF8--14677
FGF18--4736
ATP6V1G3--4739
FGF4--4827
ATP6V1H--4958
PPM1A--5058
FGF17--5059
PIK3R2--5501
NRAS--15506
RAF10.2515559
PRKAB2--5613
SHC1--5839
MAPK30.2516096
ATP6V0A4--6347
SORBS1--6543
FGF16--6612
PRKAG2--16710
FOXO10.2516970
ATP6V0E2--7188
MLST8--7510
ATP6V1G1--7665
PIK3R4--7682
FOXC2--8308
ATP6V0D2--8341
KLB--8419
STRADA--8555
PIK3C3--8907
PRKAG3--9028
ATP6V1B1--9514
FGF2--9627
STXBP4--9641
PTPN2--9960
PIK3CB--10067
PTPN11--110178
APPL1--10194
FOXO4--10242
BCAR1--10308
FGF19--10321
FGF6--10907
INSR--110986
STK11--111332
TSC20.25111448
RPTOR--12241
ATP6V1C2--12433
TLR9--12436
FRS2--12610
ATP6V1E2--12621
FOXO6--12694
HRAS0.25112845
CAB39L--13180
SH2B2--13396
ZNF106--13720
SLC2A8--13742
PHIP--13849
ATP6V0A2--14249
ATP6V1D--14824
RHOQ--15107
FOXS1--15328
MTOR--15435
FGF22--16297
TRIB3--16821
SREBF1--16874
EIF4EBP1--17707
INS--119021
EIF4EBP2--20602
STRADB--21620
TCIRG1--121664
PRKAB1--22392
FGFR4--22438
ATP6V1C1--23277
IGF20.25123391
PRKAG1--23828
THEM4--23999
CDK1--24001
DOK1--24151
PRKAA1--24385
EIF4B--24765
NR1H3--24805
EEF2K--25001
ATP6V0E1--25295
RPS6--25635

Network

GO:0008286

Network
Enrichment
NameDescriptionExternal IDs
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Entrez:7529  HGNC: 12849  Ensembl: ENSG00000166913  HPRD: 03184 
ATP6V0BATPase, H+ transporting, lysosomal 21kDa, V0 subunit b Entrez:533  Ensembl: ENSG00000117410  HGNC: 861  HPRD: 04759 
KRASKirsten rat sarcoma viral oncogene homolog Entrez:3845  Ensembl: ENSG00000133703  HGNC: 6407  HPRD: 01817 
FGFR2fibroblast growth factor receptor 2 Entrez:2263  HPRD: 01492  Ensembl: ENSG00000066468  HGNC: 3689 
FGF9fibroblast growth factor 9 Entrez:2254  HPRD: 02951  HGNC: 3687  Ensembl: ENSG00000102678 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
ATP6V0BATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
KRASKirsten rat sarcoma viral oncogene homolog
FGFR2fibroblast growth factor receptor 2
FGF9fibroblast growth factor 9
Query geneGeneGene descriptionEdge score
YWHABYWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
ATP6V0BATP6V0BATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
KRASKRASKirsten rat sarcoma viral oncogene homolog
FGFR2FGFR2fibroblast growth factor receptor 2
FGF9FGF9fibroblast growth factor 9

Troyanskaya Laboratory - Princeton University