ASD

GO:0030509 BMP signaling pathway (45)

GeneInput weightStandardRank
UBE2D3--661
CHRD--697
USP9X--950
BMPR2--1964
BMP7--987
SMAD7--1283
MSX2--11405
LEF1--1731
ACVR2A--1768
GDF6--11929
CHRDL1--1977
BMPR1A--2059
SMAD6--2079
MSX1--12365
BMPR1B--12397
GREM2--2556
SMURF2--2642
SMAD1--2829
SMAD4--2927
ACVR2B--13179
BMP10--3196
BMP6--3242
EGR1--3527
BMP2--13686
ZFYVE16--4127
SKI--4231
SMAD9--14245
RGMB--4681
SMURF1--4696
USP9Y--15087
BMP4--15180
CER1--5192
GDF7--7494
NOG--17650
FST--8021
ID1--8270
TGFBR3--8717
FSTL1--10151
SMAD5--11520
ACVR1--111780
GDF2--11942
ENG--117647
POU5F1--21422
ECSIT--23466
UBE2D1--23789

Network

GO:0030509

Network
Enrichment
NameDescriptionExternal IDs
UBE2D3ubiquitin-conjugating enzyme E2D 3 Entrez:7323  Ensembl: ENSG00000109332  HPRD: 04269  HGNC: 12476 
CHRDchordin Entrez:8646  Ensembl: ENSG00000090539  HGNC: 1949  HPRD: 04592 
USP9Xubiquitin specific peptidase 9, X-linked Entrez:8239  HGNC: 12632  HPRD: 02091  Ensembl: ENSG00000124486 
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) Entrez:659  Ensembl: ENSG00000204217  HPRD: 02880  HGNC: 1078 
BMP7bone morphogenetic protein 7 Entrez:655  Ensembl: ENSG00000101144  HGNC: 1074  HPRD: 00212 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
UBE2D3ubiquitin-conjugating enzyme E2D 3
CHRDchordin
USP9Xubiquitin specific peptidase 9, X-linked
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
BMP7bone morphogenetic protein 7
Query geneGeneGene descriptionEdge score
UBE2D3UBE2D3ubiquitin-conjugating enzyme E2D 3
CHRDCHRDchordin
USP9XUSP9Xubiquitin specific peptidase 9, X-linked
BMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
BMP7BMP7bone morphogenetic protein 7

Troyanskaya Laboratory - Princeton University