ASD

GO:0030808 regulation of nucleotide biosynthetic process (132)

GeneInput weightStandardRank
NTRK20.25128
GABBR20.25141
ADNP0.5191
ADCY2--102
ADCYAP1--127
GRM70.251147
SSTR2--185
CRHR1--280
NF10.251333
APLP1--335
GABBR10.251352
GRM3--399
CALCA--460
ADCY10.251466
DRD50.251482
GNAQ--490
ADORA1--498
NPY2R0.251597
GNAZ--618
FSHR--1648
DRD10.251662
GUCA1A--1762
OPRK10.251764
GNAL--860
ADRB1--866
GRIK30.251976
FLNA--1984
NPY1R0.2511012
CAP1--1037
ADCYAP1R1--1132
GRM80.2511152
CAP2--1213
PTHLH--11269
EDNRB--11322
VIPR2--1327
GNAI3--1340
PALM--1349
GRM2--1421
AKAP5--1517
HTR70.2511529
ADRA2A0.2511556
GNAI1--1613
HTR1A0.2511672
GUCY1A3--1730
ADRB3--11787
ADCY8--1906
MC2R--1919
MCHR10.2512005
DRD20.2512071
CALCR--2247
CHRM50.2512290
GHRHR--2312
GSK3A--2346
GNAS--12352
LHCGR0.2512362
ADCY9--2435
ABCA1--12698
DRD30.2512757
HTR4--2810
RXFP1--2904
S1PR1--2910
SPECC1L--3048
TSHR--3078
GNG7--3138
AKAP12--3150
CALCRL0.2513258
OPRD10.2513266
EDNRA--13271
MC4R0.2513280
MC5R--3358
GCGR--13430
NPR3--3798
ACR--4233
GCG--4286
ADCY5--4352
ADCY6--4362
GPR3--4384
CHRM4--4460
P2RY1--4483
AVPR2--14537
GHRH--4568
ADCY3--4618
ADORA3--4733
NTRK10.2514883
MRAP2--4941
PTH--5481
HTR1B0.2515751
GRM4--5804
GALR1--5954
GPR26--6001
MC3R0.2516322
RXFP2--16360
GNAI2--6384
S1PR3--6584
DRD40.2517058
GLP1R--7291
RGS1--7315
NPPC--7442
OPRL10.2518293
MC1R--18333
ADCY4--8354
GUCA2B--8899
SSTR50.2519084
GIPR--9148
PTGDR2--9477
EDN1--9566
ADORA2A0.2519605
UCN3--9836
MRAP--10738
GUCA1B--10950
ADORA2B--11164
CORT--11364
INSL3--111614
AVP--111615
PDZD3--12463
NOS3--12710
GALR2--12784
LTB4R2--13227
ADM2--15430
GALR3--15944
P2RY11--18359
GPR78--19507
OXER1--20000
GPR65--20238
GNA13--20348
APOE0.25121310
SLC9A3R1--21807
CCR2--22318
S1PR4--22365
ADRB20.25122718
NPR1--24360
ADCY7--25198

Network

GO:0030808

Network
Enrichment
NameDescriptionExternal IDs
NTRK2neurotrophic tyrosine kinase, receptor, type 2 Entrez:4915  Ensembl: ENSG00000148053  HPRD: 02712  HGNC: 8032 
GABBR2gamma-aminobutyric acid (GABA) B receptor, 2 Entrez:9568  Ensembl: ENSG00000136928  HGNC: 4507  HPRD: 09552 
ADNPactivity-dependent neuroprotector homeobox Entrez:23394  Ensembl: ENSG00000101126  HPRD: 09793  HGNC: 15766 
ADCY2adenylate cyclase 2 (brain) Entrez:108  HGNC: 233  HPRD: 00052  Ensembl: ENSG00000078295 
ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary) Entrez:116  HGNC: 241  HPRD: 02369  Ensembl: ENSG00000141433 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NTRK2neurotrophic tyrosine kinase, receptor, type 2
GABBR2gamma-aminobutyric acid (GABA) B receptor, 2
ADNPactivity-dependent neuroprotector homeobox
ADCY2adenylate cyclase 2 (brain)
ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary)
Query geneGeneGene descriptionEdge score
NTRK2NTRK2neurotrophic tyrosine kinase, receptor, type 2
GABBR2GABBR2gamma-aminobutyric acid (GABA) B receptor, 2
ADNPADNPactivity-dependent neuroprotector homeobox
ADCY2ADCY2adenylate cyclase 2 (brain)
ADCYAP1ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary)

Troyanskaya Laboratory - Princeton University