ASD

GO:0007172 signal complex assembly (24)

GeneInput weightStandardRank
GRIK20.51142
CACNA1A--1231
MAGI2--252
MAPK8IP2--275
DLG20.251284
GRIN2B1.01599
DLG4--707
GRIK5--890
FLNA--1984
LRP4--1290
MUSK--2237
SRC--2241
CDK50.2513113
PTK2B--3191
NCK2--4595
PXN--5215
AGRN0.2515611
SMO0.2515864
CD3E--8226
NCK1--10453
PTK20.25111177
PICK1--11571
DVL1P1--19166
DVL1--21155

Network

GO:0007172

Network
Enrichment
NameDescriptionExternal IDs
GRIK2glutamate receptor, ionotropic, kainate 2 Entrez:2898  Ensembl: ENSG00000164418  HGNC: 4580  HPRD: 00692 
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit Entrez:773  HPRD: 03004  HGNC: 1388  Ensembl: ENSG00000141837 
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 2 Entrez:9863  Ensembl: ENSG00000187391  HGNC: 18957  HPRD: 16212 
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2 Entrez:23542  HPRD: 09674  Ensembl: ENSG00000008735  HGNC: 6883 
DLG2discs, large homolog 2 (Drosophila) Entrez:1740  Ensembl: ENSG00000150672  HGNC: 2901  HPRD: 08220 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GRIK2glutamate receptor, ionotropic, kainate 2
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 2
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2
DLG2discs, large homolog 2 (Drosophila)
Query geneGeneGene descriptionEdge score
GRIK2GRIK2glutamate receptor, ionotropic, kainate 2
CACNA1ACACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
MAGI2MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 2
MAPK8IP2MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2
DLG2DLG2discs, large homolog 2 (Drosophila)

Troyanskaya Laboratory - Princeton University