ASD

GO:0040013 negative regulation of locomotion (101)

GeneInput weightStandardRank
SLIT1--33
PLCB1--161
GRM50.251196
SFRP1--204
ABR--211
NF10.251333
DRD50.251482
ADORA1--498
SLIT2--582
RAP2A--652
DRD10.251662
CHRD--697
THY1--993
PTPRK--1053
DLC1--1105
ROBO2--11224
SMAD7--1283
AGTR20.2511418
TBX5--1743
ROBO1--1888
PTPRU--1921
NRP1--1961
DRD20.2512071
SEMA3A--2076
VASH10.2512133
PTEN1.012260
NKX2-1--2488
GREM1--2654
IGFBP5--2665
HDAC5--2683
SRF--2700
BCR--12801
MCC--2843
WNT5A--2870
ILK--2917
RAP2C--3043
SPECC1L--3048
BMP10--3196
GATA3--3207
TRIB1--3331
CITED2--3457
PTPRM--3512
DAB2IP--3635
DAG1--3662
SFRP2--3758
NISCH--3766
HOXA7--4063
WNT11--4528
NR2F2--4609
NF2--14798
WNT3--4799
ADIPOQ0.2514834
WNT3A--4844
DLL4--5152
MIA3--5434
PODN--5712
ARAP3--6203
PTPRJ--17218
ANGPT2--7366
ABHD6--7605
NOG--17650
CX3CR1--7884
PIN1--8222
ROBO40.2518616
TGFBR3--8717
GHRL0.2519333
ANGPT4--9561
TIE1--9601
ADORA2A0.2519605
FGF2--9627
EGFL7--10251
IL33--11000
APOH--11155
ELANE--111717
GDF2--11942
ABHD2--12003
PDGFB--12484
RYK--12768
SCAI--12809
IGFBP3--13922
ACVRL1--114027
TGFB10.25114736
C5--115436
RAP2B--15525
SHH--115942
CLIC4--16075
HMOX1--20520
VCL--120649
SERPINE10.25120720
KRIT1--20970
APOE0.25121310
SLC9A3R1--21807
THBS1--21993
LRP1--22904
RNF20--22923
TPM1--123549
ADA0.5124175
GTPBP4--24260
ALOX15B--24304
RRAS--24498
CNN2--24698

Network

GO:0040013

Network
Enrichment
NameDescriptionExternal IDs
SLIT1slit homolog 1 (Drosophila) Entrez:6585  Ensembl: ENSG00000187122  HGNC: 11085  HPRD: 04773 
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
GRM5glutamate receptor, metabotropic 5 Entrez:2915  HGNC: 4597  Ensembl: ENSG00000168959 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
ABRactive BCR-related Entrez:29  HGNC: 81  HPRD: 02649  Ensembl: ENSG00000159842 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SLIT1slit homolog 1 (Drosophila)
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
GRM5glutamate receptor, metabotropic 5
SFRP1secreted frizzled-related protein 1
ABRactive BCR-related
Query geneGeneGene descriptionEdge score
SLIT1SLIT1slit homolog 1 (Drosophila)
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
GRM5GRM5glutamate receptor, metabotropic 5
SFRP1SFRP1secreted frizzled-related protein 1
ABRABRactive BCR-related

Troyanskaya Laboratory - Princeton University