ASD

GO:0051963 regulation of synaptogenesis (24)

GeneInput weightStandardRank
SNAP250.2516
SLIT1--33
ADNP0.5191
ASIC20.251105
GRIN1--167
NLGN10.251265
SYNDIG1--1073
UBE2V2--1207
ROBO2--11224
GHSR0.2512085
MUSK--2237
PVRL1--2493
WNT5A--2870
NLGN31.013428
OXTR0.514494
AGRN0.2515611
NLGN2--6159
WNT7A--6375
THBS2--7963
GHRL0.2519333
OXT0.25110022
PTK20.25111177
PDLIM5--11934
CHRNB20.25120277

Network

GO:0051963

Network
Enrichment
NameDescriptionExternal IDs
SNAP25synaptosomal-associated protein, 25kDa Entrez:6616  Ensembl: ENSG00000132639  HPRD: 02637  HGNC: 11132 
SLIT1slit homolog 1 (Drosophila) Entrez:6585  Ensembl: ENSG00000187122  HGNC: 11085  HPRD: 04773 
ADNPactivity-dependent neuroprotector homeobox Entrez:23394  Ensembl: ENSG00000101126  HPRD: 09793  HGNC: 15766 
ASIC2acid-sensing (proton-gated) ion channel 2 Entrez:40  HGNC: 99  HPRD: 03471  Ensembl: ENSG00000108684 
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1 Entrez:2902  HGNC: 4584  HPRD: 15926  Ensembl: ENSG00000176884 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SNAP25synaptosomal-associated protein, 25kDa
SLIT1slit homolog 1 (Drosophila)
ADNPactivity-dependent neuroprotector homeobox
ASIC2acid-sensing (proton-gated) ion channel 2
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1
Query geneGeneGene descriptionEdge score
SNAP25SNAP25synaptosomal-associated protein, 25kDa
SLIT1SLIT1slit homolog 1 (Drosophila)
ADNPADNPactivity-dependent neuroprotector homeobox
ASIC2ASIC2acid-sensing (proton-gated) ion channel 2
GRIN1GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1

Troyanskaya Laboratory - Princeton University