ASD

GO:0030111 regulation of Wnt receptor signaling pathway (141)

GeneInput weightStandardRank
PPP2CA--21
SOX2--1125
FGFR2--1165
SFRP1--204
FGF9--241
CDK140.251334
SALL1--408
APC0.251528
SOX4--581
EDA--1615
APC2--671
DISC10.251723
LRP6--778
CSNK1D--811
PPP2R1A--852
NLK--1019
WNT10B--1030
SOX9--11045
WNT2B--1126
CSNK1E0.2511225
LRP4--1290
HMGXB4--1301
HDAC2--1413
CXXC4--1472
SMAD3--1541
AES--1548
UBR5--1553
FGFR3--11648
LEF1--1731
SIX3--11742
WNT20.2511783
CITED1--1867
TNKS--1911
MACF1--1938
GRB10--2023
TLE1--2072
DKK2--2075
DLX5--2361
MCC--2843
WNT5A--2870
ILK--2917
USP34--2985
MED120.2513028
LATS1--3031
LECT2--3370
RSPO2--3476
SOX17--3484
SFRP4--3511
EGR1--3527
DAB2IP--3635
SFRP2--3758
DKK3--4056
FOXL1--4171
SKI--4231
FGF10--14373
DIXDC1--4469
WNT11--4528
DRAXIN--4545
ZEB2--4607
SOX7--4709
WNT3A--4844
BARX1--4860
MBD2--4876
SIAH2--4934
PPM1A--5058
WWOX--15122
GPC3--15153
PRICKLE1--15311
NKX2-50.2515490
TCF7L2--15670
SOST--5795
RSPO1--5850
CYLD--15851
AXIN2--15927
STK4--6010
CTNNBIP1--6252
WNT7A--6375
ZNF703--6470
GLI1--6597
DKK4--6622
CTNND1--6834
DKK1--6892
TBX18--7034
WNT8A--7061
CHD81.017247
BAMBI--7548
TLE2--7919
CAPRIN2--8066
GSC--8075
ZRANB1--8282
TAX1BP3--8734
GLI3--19032
TNKS2--9062
APCDD1--9391
FRZB--9553
HNF1B--19562
SFRP5--9913
PPAP2B--10712
AXIN1--110905
MESP1--10948
KREMEN1--11168
STK11--111332
TSC20.25111448
WNT5B--11732
MDFI--11799
HHEX--12438
JUP--112627
TLR2--112838
DDIT3--12944
TCF7L1--13850
NPHP3--114055
MDFIC--14627
CCNY--14714
LATS2--15008
NRARP--15165
SHH--115942
WLS--16366
LRP5--116985
FZD6--19825
NFKB1--20216
RNF146--20728
DVL1--21155
POU5F1--21422
WNT4--21840
TRPM4--21966
FZD1--22086
INVS--122094
STK3--22605
WWTR1--22777
YAP1--22816
GNB2L1--22873
LRP1--22904
SNAI2--122934
SENP2--23540
PFDN5--23979
EMD--124154
SCYL2--24230
COL1A1--124560
CAV1--124767
CBY1--24830
DAB2--24837

Network

GO:0030111

Network
Enrichment
NameDescriptionExternal IDs
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme Entrez:5515  HGNC: 9299  HPRD: 08912 
SOX2SRY (sex determining region Y)-box 2 Entrez:6657  HGNC: 11195  HPRD: 08921  Ensembl: ENSG00000181449 
FGFR2fibroblast growth factor receptor 2 Entrez:2263  HPRD: 01492  Ensembl: ENSG00000066468  HGNC: 3689 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
FGF9fibroblast growth factor 9 Entrez:2254  HPRD: 02951  HGNC: 3687  Ensembl: ENSG00000102678 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
SOX2SRY (sex determining region Y)-box 2
FGFR2fibroblast growth factor receptor 2
SFRP1secreted frizzled-related protein 1
FGF9fibroblast growth factor 9
Query geneGeneGene descriptionEdge score
PPP2CAPPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
SOX2SOX2SRY (sex determining region Y)-box 2
FGFR2FGFR2fibroblast growth factor receptor 2
SFRP1SFRP1secreted frizzled-related protein 1
FGF9FGF9fibroblast growth factor 9

Troyanskaya Laboratory - Princeton University