ASD

GO:0046887 positive regulation of hormone secretion (59)

GeneInput weightStandardRank
SNAP250.2516
SOX11--66
PRKCE--156
CRH--328
GABBR10.251352
NNAT--382
PEX5L--531
CCKBR--533
SOX4--581
CREB1--991
IRS1--11052
ISL1--1441
EDN3--11522
IRS2--11607
BAD--1647
ACVR2A--1768
DRD20.2512071
RBP4--2097
TRH--2296
GHRHR--2312
GLUD1--12592
INHBB--2840
GCK--12874
NKX6-1--3174
INHA--3229
MGEA5--3440
OXCT1--3898
GIP--3965
GCG--4286
P2RY1--4483
GHRH--4568
PFKFB2--5518
TCF7L2--15670
SLC30A8--15810
CAPN10--7136
GLP1R--7291
APLN--7473
TNFSF11--17511
CCKAR--7616
RAB8B--8016
KISS1R--8159
BLK--18856
AACS--9069
GIPR--9148
DOC2B--9220
GHRL0.2519333
EDN1--9566
INHBA--9731
UCN3--9836
FFAR1--10658
HCAR2--12026
SERP1--13167
EDN2--13347
LEP0.25113368
PSMD9--13761
NR0B2--114446
NMU--16499
CD380.25117453
LIF--20888

Network

GO:0046887

Network
Enrichment
NameDescriptionExternal IDs
SNAP25synaptosomal-associated protein, 25kDa Entrez:6616  Ensembl: ENSG00000132639  HPRD: 02637  HGNC: 11132 
SOX11SRY (sex determining region Y)-box 11 Entrez:6664  HGNC: 11191  Ensembl: ENSG00000176887  HPRD: 02940 
PRKCEprotein kinase C, epsilon Entrez:5581  HPRD: 01500  HGNC: 9401  Ensembl: ENSG00000171132 
CRHcorticotropin releasing hormone Entrez:1392  Ensembl: ENSG00000147571  HPRD: 07172  HGNC: 2355 
GABBR1gamma-aminobutyric acid (GABA) B receptor, 1 Entrez:2550  HGNC: 4070  Ensembl: ENSG00000204681  HPRD: 04644 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SNAP25synaptosomal-associated protein, 25kDa
SOX11SRY (sex determining region Y)-box 11
PRKCEprotein kinase C, epsilon
CRHcorticotropin releasing hormone
GABBR1gamma-aminobutyric acid (GABA) B receptor, 1
Query geneGeneGene descriptionEdge score
SNAP25SNAP25synaptosomal-associated protein, 25kDa
SOX11SOX11SRY (sex determining region Y)-box 11
PRKCEPRKCEprotein kinase C, epsilon
CRHCRHcorticotropin releasing hormone
GABBR1GABBR1gamma-aminobutyric acid (GABA) B receptor, 1

Troyanskaya Laboratory - Princeton University