ASD

GO:0051351 positive regulation of ligase activity (83)

GeneInput weightStandardRank
PSMA1--42
PSMB3--79
PSMA4--95
PSMD14--120
PSMD8--144
PSMA5--219
PSMB1--318
PSMA3--373
PSMC4--380
PSMC6--405
PSMB7--554
PSMB4--562
PSMD2--595
UBE2N--693
PSMB6--696
UBE2S--748
PSMA7--782
PSMC3--794
PSMC5--831
PSMD1--867
PSMD6--884
PSMC1--904
PSMD3--909
PSMD11--943
PSMC2--952
CUL1--972
PSMD13--994
PSMD4--1166
PSMA6--1492
PSME4--1576
PSMA2--1693
PSMD10--2012
PSMD12--2120
BMI1--2175
PTEN1.012260
PSMD7--2386
BTRC--2430
CDC14B--2703
FZR1--3987
UBC--5781
SKP1--6164
UBE2E1--6513
PSME2--7488
PSMB9--7654
PSMB2--7801
PSMA8--8114
PIN1--8222
MID1IP1--8619
ANAPC2--8902
CDC23--9012
AXIN1--110905
ANAPC10--11143
PSME1--11612
PSMB8--12378
ANAPC11--13665
PSMD9--13761
PSMB11--14440
PSMB10--14502
CDC27--14913
TRIB3--16821
PSME3--17451
PSMD5--18391
CDC26--21067
NHEJ1--21873
UBB--22223
RPS27A--22920
PSMF1--22952
UBE2D1--23789
CDK1--24001
UBA52--24116
PSMB5--24489
GCLM--24501
CCNB1--24648
ANAPC7--24876
CDC20--24914
ANAPC5--24931
XRCC4--24940
ANAPC4--25215
UBE2C--25279
CDC16--25415
FBXO5--25430
ANAPC1--25548
PLK1--25689

Network

GO:0051351

Network
Enrichment
NameDescriptionExternal IDs
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1 Entrez:5682  Ensembl: ENSG00000129084  HPRD: 04170  HGNC: 9530 
PSMB3proteasome (prosome, macropain) subunit, beta type, 3 Entrez:5691  HPRD: 03709  Ensembl: ENSG00000108294  HGNC: 9540 
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4 Entrez:5685  Ensembl: ENSG00000041357  HPRD: 10168  HGNC: 9533 
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 Entrez:10213  HGNC: 16889  Ensembl: ENSG00000115233  HPRD: 06208 
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 Entrez:5714  Ensembl: ENSG00000099341  HPRD: 10171  HGNC: 9566 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMB3proteasome (prosome, macropain) subunit, beta type, 3
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
Query geneGeneGene descriptionEdge score
PSMA1PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMB3PSMB3proteasome (prosome, macropain) subunit, beta type, 3
PSMA4PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
PSMD14PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD8PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8

Troyanskaya Laboratory - Princeton University