ASD

GO:0046058 cAMP metabolic process (26)

GeneInput weightStandardRank
ADCY2--102
PDE4D--357
ADCY10.251466
GNAL--860
PDE4A--1000
PTHLH--11269
PDE2A--1591
PDE4B--1754
PDE1B--1791
ADCY8--1906
PDE11A--2107
ADCY10--2222
GNAS--12352
ADCY9--2435
PDE3A--3024
PDE3B--3088
PDE4C--4298
ADCY5--4352
ADCY6--4362
ADCY3--4618
PTH--5481
ADCY4--8354
ADORA2A0.2519605
UCN2--9660
ADM--10761
ADCY7--25198

Network

GO:0046058

Network
Enrichment
NameDescriptionExternal IDs
ADCY2adenylate cyclase 2 (brain) Entrez:108  HGNC: 233  HPRD: 00052  Ensembl: ENSG00000078295 
PDE4Dphosphodiesterase 4D, cAMP-specific Entrez:5144  HPRD: 02530  HGNC: 8783  Ensembl: ENSG00000113448 
ADCY1adenylate cyclase 1 (brain) Entrez:107  HGNC: 232  HPRD: 00053  Ensembl: ENSG00000164742 
GNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type Entrez:2774  HGNC: 4388  Ensembl: ENSG00000141404  HPRD: 00758 
PDE4Aphosphodiesterase 4A, cAMP-specific Entrez:5141  HPRD: 02527  HGNC: 8780  Ensembl: ENSG00000065989 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ADCY2adenylate cyclase 2 (brain)
PDE4Dphosphodiesterase 4D, cAMP-specific
ADCY1adenylate cyclase 1 (brain)
GNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
PDE4Aphosphodiesterase 4A, cAMP-specific
Query geneGeneGene descriptionEdge score
ADCY2ADCY2adenylate cyclase 2 (brain)
PDE4DPDE4Dphosphodiesterase 4D, cAMP-specific
ADCY1ADCY1adenylate cyclase 1 (brain)
GNALGNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
PDE4APDE4Aphosphodiesterase 4A, cAMP-specific

Troyanskaya Laboratory - Princeton University