ASD

GO:0051051 negative regulation of transport (211)

GeneInput weightStandardRank
GNAO1--3
CNR10.25110
YWHAB0.25145
HTR2A0.25151
GRM70.251147
ABCC8--1161
CALM3--195
SFRP1--204
ABR--211
PPP3CA--278
NRG10.251285
AKT10.251303
PDE8B--1323
NF10.251333
GABBR10.251352
SNCA--1401
CALCA--460
KCNA5--1477
PLCB4--494
ADORA1--498
NPY5R0.251512
IL1RAPL10.251519
SOX4--581
G3BP2--608
NEDD4L--670
APC2--671
CALM1--708
TXN--803
CX3CL1--832
NOS10.251908
ERBB3--921
PKIA--959
FLNA--1984
BMP7--987
NPY1R0.2511012
IRS1--11052
RAC1--1087
CARTPT0.2511181
AKAP5--1517
EDN3--11522
ADRA2A0.2511556
IRS2--11607
FBXW11--1610
SCAMP50.2511910
PSMD10--2012
GRB10--2023
DRD20.2512071
GHSR0.2512085
TRH--2296
GSK3A--2346
CALM2--2360
NCS1--2387
PEA15--2463
SLC18A1--2477
DRD30.2512757
BCR--12801
INHBB--2840
MXI1--12895
SERPINE2--2896
FGF23--12939
AKT2--13025
LATS1--3031
FOXF1--13053
PDE3B--3088
CDK50.2513113
PFKL--3172
PTGS20.2513176
INHA--3229
OPRD10.2513266
NOTCH1--13360
SFRP4--3511
DAB2IP--3635
PICALM--14018
NLRP30.2514091
BARD1--14151
ACVR1C--4200
PDE4C--4298
NDFIP1--4331
ARF6--4366
ITGB30.514442
KIAA0226--4470
P2RY1--4483
OXTR0.514494
AVPR2--14537
IL6--14578
BEST3--4593
MAPK7--4626
PXK--4731
SIRT4--4743
ADIPOQ0.2514834
PACSIN1--5061
MAOB0.2515190
CIDEA--5234
STIM2--5530
ENPP1--15674
IFNA2--5752
CYLD--15851
AXIN2--15927
TNFSF4--6034
NFKBIA--6067
IL1B--16220
FOXP3--16270
KEAP1--6336
GNAI2--6384
SRGN--6476
ADRA2C--6524
NR1H2--6604
KCNJ11--16868
CRYAA--6901
DRD40.2517058
IL11--7322
ABCG8--7325
SLC18A2--7407
HCRT0.2517434
SYTL4--7445
ANXA1--7465
IL10--17883
FST--8021
KCNQ1--18097
ADRA2B--8196
AKAP1--8358
MTMR2--18529
SERGEF--8722
EGF0.2518839
GHRL0.2519333
EDN1--9566
UCN2--9660
INHBA--9731
SFRP5--9913
RHOC--9929
OXT0.25110022
TRAT1--10346
FFAR4--10349
STXBP3--10747
INSR--110986
IL33--11000
NDFIP2--11428
ABCG5--11513
APOC2--11692
MDFI--11799
UTS2R--11874
APOA1--111900
WWP2--12103
UACA--12262
HNF4A--112281
EPO--12314
APOA2--12739
LRSAM1--12996
TACC3--13022
REST--13067
EDN2--13347
LEP0.25113368
PKDCC--13669
PSMD9--13761
ICAM1--14063
SLC30A1--14226
PLA2G10--14358
NFKBIE--14547
MDFIC--14627
CRBN--14635
TGFB10.25114736
F2RL1--15088
FAM3D--15418
MTOR--15435
C5--115436
YRDC--15598
GOPC--16236
SREBF1--16874
NLRP12--16984
INS--119021
APOC3--19472
TNF0.25119823
OSM--19901
PKIG--20074
TONSL--20185
NFKB1--20216
PACSIN3--20292
HMOX1--20520
LIF--20888
TNFRSF4--20950
NFKBIL1--21296
APOC1--21328
NEDD40.25121604
BTN2A2--21737
SLC9A3R1--21807
THBS1--21993
FZD1--22086
CCR2--22318
NFKBIB--22383
RHBDF2--22619
CD74--22633
ADRB20.25122718
CD36--22749
WWTR1--22777
GNB2L1--22873
SNAI2--122934
PTGS1--23458
ANPEP--23922
FAF1--24152
EMD--124154
ADA0.5124175
RSC1A1--24337
RHBDF1--24539
CNN2--24698
NR1H3--24805
IL1RN0.25124819
CRYAB--124949
DPH3--25120
HADH--125281
ITGAV--25348
ARL6IP5--25515

Network

GO:0051051

Network
Enrichment
NameDescriptionExternal IDs
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O Entrez:2775  HPRD: 00757  HGNC: 4389  Ensembl: ENSG00000087258 
CNR1cannabinoid receptor 1 (brain) Entrez:1268  HGNC: 2159  Ensembl: ENSG00000118432  HPRD: 00259 
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Entrez:7529  HGNC: 12849  Ensembl: ENSG00000166913  HPRD: 03184 
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Entrez:3356  HPRD: 01638  Ensembl: ENSG00000102468  HGNC: 5293 
GRM7glutamate receptor, metabotropic 7 Entrez:2917  HGNC: 4599  Ensembl: ENSG00000196277  HPRD: 04979 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
CNR1cannabinoid receptor 1 (brain)
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
GRM7glutamate receptor, metabotropic 7
Query geneGeneGene descriptionEdge score
GNAO1GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
CNR1CNR1cannabinoid receptor 1 (brain)
YWHABYWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
HTR2AHTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
GRM7GRM7glutamate receptor, metabotropic 7

Troyanskaya Laboratory - Princeton University