ASD

GO:0050807 regulation of synapse organization (32)

GeneInput weightStandardRank
SNAP250.2516
SLIT1--33
NEUROD2--68
ADNP0.5191
ASIC20.251105
NCAN--158
GRIN1--167
NLGN10.251265
CTNNA2--654
SYNDIG1--1073
UBE2V2--1207
ROBO2--11224
GHSR0.2512085
FRMPD4--2091
MUSK--2237
PVRL1--2493
WNT5A--2870
NLGN31.013428
OXTR0.514494
AGRN0.2515611
NLGN2--6159
WNT7A--6375
THBS2--7963
ANAPC2--8902
GHRL0.2519333
OXT0.25110022
PTK20.25111177
ARHGEF15--11779
PDLIM5--11934
CHRNB20.25120277
KLK8--22103
CDC20--24914

Network

GO:0050807

Network
Enrichment
NameDescriptionExternal IDs
SNAP25synaptosomal-associated protein, 25kDa Entrez:6616  Ensembl: ENSG00000132639  HPRD: 02637  HGNC: 11132 
SLIT1slit homolog 1 (Drosophila) Entrez:6585  Ensembl: ENSG00000187122  HGNC: 11085  HPRD: 04773 
NEUROD2neuronal differentiation 2 Entrez:4761  HPRD: 03429  HGNC: 7763 
ADNPactivity-dependent neuroprotector homeobox Entrez:23394  Ensembl: ENSG00000101126  HPRD: 09793  HGNC: 15766 
ASIC2acid-sensing (proton-gated) ion channel 2 Entrez:40  HGNC: 99  HPRD: 03471  Ensembl: ENSG00000108684 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SNAP25synaptosomal-associated protein, 25kDa
SLIT1slit homolog 1 (Drosophila)
NEUROD2neuronal differentiation 2
ADNPactivity-dependent neuroprotector homeobox
ASIC2acid-sensing (proton-gated) ion channel 2
Query geneGeneGene descriptionEdge score
SNAP25SNAP25synaptosomal-associated protein, 25kDa
SLIT1SLIT1slit homolog 1 (Drosophila)
NEUROD2NEUROD2neuronal differentiation 2
ADNPADNPactivity-dependent neuroprotector homeobox
ASIC2ASIC2acid-sensing (proton-gated) ion channel 2

Troyanskaya Laboratory - Princeton University