ASD

GO:0060627 regulation of vesicle-mediated transport (150)

GeneInput weightStandardRank
SYT1--5
VAMP2--57
PLCB1--161
AP2S1--110
AMPH--118
CADPS--119
SYNJ1--178
ABR--211
CACNA1A--1231
CRHR1--280
SH3GL2--301
SNCA--1401
SNAP91--428
PFN2--431
STX1A0.251449
IL1RAPL10.251519
RAB3A0.251520
RAPGEF40.251635
STXBP1--659
NEDD4L--670
CLIP3--739
HNRNPK--746
BICD1--760
CDH13--1072
RAC1--1087
TUB0.2511090
SGIP1--1331
ACTN4--11332
EPN2--1376
ADRA2A0.2511556
RAB3B--1562
SYT7--1604
DOC2A0.2511649
SEPT5--1818
SCAMP50.2511910
CALY--1915
HIP1--1990
USP6--2039
DRD20.2512071
RAB26--2115
GLRA1--2146
RAB5C--2180
CD47--2375
NCS1--2387
CBL--2611
GATA2--12710
BCR--12801
FOXF1--13053
RALB--3082
MIB1--3110
CDK50.2513113
LGI3--3320
NOTCH1--13360
ANGPT1--3376
SFRP4--3511
STX1B--3638
GAB2--3859
RAB3C--3874
PTX3--3914
CACNA1H1.013918
PICALM--14018
ZFYVE16--4127
BIN1--4255
ARF6--4366
ITGB1--4390
KIAA0226--4470
ADIPOQ0.2514834
WNT3A--4844
PACSIN1--5061
GPC3--15153
SYT9--5308
RALA--5445
SNX17--5691
SLC30A8--15810
RSPO1--5850
STON1--5860
STON2--5933
STXBP5--5936
SFTPD--6534
NR1H2--6604
DKK1--6892
NSF--6991
TRPV6--7049
RPH3AL--7341
MBL2--7432
ANXA1--7465
PCSK9--8260
TULP1--18262
AHSG--8418
MTMR2--18529
DOC2B--9220
ANXA2--9301
VTN--9385
FGF2--9627
PPT1--110364
MS4A2--10551
SELE--10573
STXBP3--10747
NAPB--11425
TSC20.25111448
SCARB1--11598
APOC2--11692
CCL19--11890
SPACA3--12042
SCFD1--12149
CNST--12561
ZP4--12785
LRSAM1--12996
APOA5--113056
REST--13067
RAB27B--13114
PKDCC--13669
AZU1--14133
RSG1--14224
TGFB10.25114736
F2RL1--15088
ZP3--15811
GOPC--16236
OPHN10.5116404
RAB4A--17249
FCER1G--17885
PLA2G4A--18503
CCL21--19130
APOC3--19472
SLC11A1--19965
PACSIN3--20292
STXBP2--120456
HMOX1--20520
SERPINE10.25120720
RAB3D--20932
APOC1--21328
CBLL1--21704
B4GALT1--121783
CCR2--22318
CALR--22356
EHD4--22484
NOD2--122677
UNC13D--122679
CD36--22749
GNB2L1--22873
PLD2--23098
NCKAP1L--23440
SYK--23795
C3--124089
SCYL2--24230
CNN2--24698
CAV1--124767
NR1H3--24805
LDLRAP1--25301
ITGAV--25348

Network

GO:0060627

Network
Enrichment
NameDescriptionExternal IDs
SYT1synaptotagmin I Entrez:6857  HPRD: 01710  HGNC: 11509  Ensembl: ENSG00000067715 
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2) Entrez:6844  HGNC: 12643  HPRD: 01717  Ensembl: ENSG00000220205 
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
AP2S1adaptor-related protein complex 2, sigma 1 subunit Entrez:1175  HPRD: 03762  Ensembl: ENSG00000042753  HGNC: 565 
AMPHamphiphysin Entrez:273  HPRD: 02687  Ensembl: ENSG00000078053  HGNC: 471 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SYT1synaptotagmin I
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
AP2S1adaptor-related protein complex 2, sigma 1 subunit
AMPHamphiphysin
Query geneGeneGene descriptionEdge score
SYT1SYT1synaptotagmin I
VAMP2VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
AP2S1AP2S1adaptor-related protein complex 2, sigma 1 subunit
AMPHAMPHamphiphysin

Troyanskaya Laboratory - Princeton University