ASD

GO:0010579 positive regulation of adenylate cyclase activity by G-protein signaling pathway (47)

GeneInput weightStandardRank
ADCY2--102
CRHR1--280
CALCA--460
ADCY10.251466
DRD50.251482
GNAQ--490
FSHR--1648
DRD10.251662
GNAL--860
ADRB1--866
PTHLH--11269
HTR70.2511529
ADRB3--11787
ADCY8--1906
CALCR--2247
GHRHR--2312
GNAS--12352
ADCY9--2435
DRD30.2512757
HTR4--2810
RXFP1--2904
SPECC1L--3048
TSHR--3078
CALCRL0.2513258
GCGR--13430
ADCY5--4352
ADCY6--4362
GPR3--4384
GHRH--4568
ADCY3--4618
PTH--5481
GALR1--5954
GPR26--6001
RXFP2--16360
GLP1R--7291
ADCY4--8354
GIPR--9148
ADORA2A0.2519605
UCN3--9836
GALR2--12784
ADM2--15430
GPR78--19507
GNA13--20348
SLC9A3R1--21807
S1PR4--22365
ADRB20.25122718
ADCY7--25198

Network

GO:0010579

Network
Enrichment
NameDescriptionExternal IDs
ADCY2adenylate cyclase 2 (brain) Entrez:108  HGNC: 233  HPRD: 00052  Ensembl: ENSG00000078295 
CRHR1corticotropin releasing hormone receptor 1 Entrez:1394  Ensembl: ENSG00000120088  HGNC: 2357  HPRD: 08830 
CALCAcalcitonin-related polypeptide alpha Entrez:796  HGNC: 1437  HPRD: 00238  Ensembl: ENSG00000110680 
ADCY1adenylate cyclase 1 (brain) Entrez:107  HGNC: 232  HPRD: 00053  Ensembl: ENSG00000164742 
DRD5dopamine receptor D5 Entrez:1816  HGNC: 3026  Ensembl: ENSG00000169676  HPRD: 00542 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ADCY2adenylate cyclase 2 (brain)
CRHR1corticotropin releasing hormone receptor 1
CALCAcalcitonin-related polypeptide alpha
ADCY1adenylate cyclase 1 (brain)
DRD5dopamine receptor D5
Query geneGeneGene descriptionEdge score
ADCY2ADCY2adenylate cyclase 2 (brain)
CRHR1CRHR1corticotropin releasing hormone receptor 1
CALCACALCAcalcitonin-related polypeptide alpha
ADCY1ADCY1adenylate cyclase 1 (brain)
DRD5DRD5dopamine receptor D5

Troyanskaya Laboratory - Princeton University