ASD

GO:0017157 regulation of exocytosis (59)

GeneInput weightStandardRank
SYT1--5
VAMP2--57
PLCB1--161
CADPS--119
ABR--211
CACNA1A--1231
CRHR1--280
SNCA--1401
PFN2--431
STX1A0.251449
IL1RAPL10.251519
RAB3A0.251520
RAPGEF40.251635
STXBP1--659
ADRA2A0.2511556
RAB3B--1562
SYT7--1604
DOC2A0.2511649
SEPT5--1818
SCAMP50.2511910
RAB26--2115
GLRA1--2146
NCS1--2387
BCR--12801
FOXF1--13053
RALB--3082
CDK50.2513113
LGI3--3320
NOTCH1--13360
STX1B--3638
GAB2--3859
RAB3C--3874
CACNA1H1.013918
SYT9--5308
RALA--5445
STXBP5--5936
NSF--6991
TRPV6--7049
RPH3AL--7341
DOC2B--9220
FGF2--9627
MS4A2--10551
STXBP3--10747
NAPB--11425
ZP4--12785
REST--13067
RAB27B--13114
RSG1--14224
F2RL1--15088
ZP3--15811
FCER1G--17885
STXBP2--120456
HMOX1--20520
RAB3D--20932
B4GALT1--121783
CCR2--22318
UNC13D--122679
PLD2--23098
SYK--23795

Network

GO:0017157

Network
Enrichment
NameDescriptionExternal IDs
SYT1synaptotagmin I Entrez:6857  HPRD: 01710  HGNC: 11509  Ensembl: ENSG00000067715 
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2) Entrez:6844  HGNC: 12643  HPRD: 01717  Ensembl: ENSG00000220205 
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
CADPSCa++-dependent secretion activator Entrez:8618  Ensembl: ENSG00000163618  HGNC: 1426  HPRD: 05236 
ABRactive BCR-related Entrez:29  HGNC: 81  HPRD: 02649  Ensembl: ENSG00000159842 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SYT1synaptotagmin I
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
CADPSCa++-dependent secretion activator
ABRactive BCR-related
Query geneGeneGene descriptionEdge score
SYT1SYT1synaptotagmin I
VAMP2VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
CADPSCADPSCa++-dependent secretion activator
ABRABRactive BCR-related

Troyanskaya Laboratory - Princeton University