ASD

GO:0008016 regulation of heart contraction (89)

GeneInput weightStandardRank
GNAO1--3
CACNA1G0.251149
CACNA1B--319
KCNH2--1390
KCNIP2--426
CALCA--460
ADORA1--498
SP4--515
TAC10.251543
TGFB2--625
THRB--1735
RYR2--1862
ADRB1--866
NOS10.251908
ADRA1A--937
HDAC4--963
PIK3R10.2511065
CELF2--1278
SMAD7--1283
AGTR20.2511418
EDN3--11522
ATP1A2--11611
CHRNA70.511657
FKBP1B--1700
KCNJ12--1925
DRD20.2512071
SEMA3A--2076
CHRM2--2223
GSK3A--2346
TACR3--2526
HBEGF--2652
HCN2--3076
AVPR1A0.513141
RGS2--3677
SCN5A--13759
ADRA1D--3761
CACNA1H1.013918
HOPX--4054
ATP1A10.2514084
KCNE1--14341
AVPR1B0.2514502
KCNE1L--4641
ADORA3--4733
ADRBK1--4864
IRX5--5001
EPAS1--5248
IFNG--15255
NKX2-50.2515490
TNNT2--15818
IL2--5825
ADRA1B0.2515964
MEF2A--6060
TH0.2516482
KCNE2--16837
PLN0.2517018
GLP1R--7291
APLN--7473
CSRP3--17844
KCNQ1--18097
GJA10.2518195
FOXN4--8243
PDE5A--8315
GAA--18353
MYH6--19135
CYP2J2--9192
EDN1--9566
OXT0.25110022
CAV3--110580
ADM--10761
S100A1--11072
PEBP1--11226
PMCH--11242
KCNG2--11544
EDN2--13347
MYH7--113461
MYL3--113896
SRI--15085
DMPK0.25116840
SREBF1--16874
DES--117512
P2RX4--20526
CHRFAM7A--21295
CTGF--21927
HSPB7--22378
ADRB20.25122718
TPM1--123549
ADA0.5124175
GLRX3--24919
MYL4--25557

Network

GO:0008016

Network
Enrichment
NameDescriptionExternal IDs
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O Entrez:2775  HPRD: 00757  HGNC: 4389  Ensembl: ENSG00000087258 
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit Entrez:8913  HPRD: 04961  HGNC: 1394  Ensembl: ENSG00000006283 
CACNA1Bcalcium channel, voltage-dependent, N type, alpha 1B subunit Entrez:774  HPRD: 03005  Ensembl: ENSG00000148408  HGNC: 1389 
KCNH2potassium voltage-gated channel, subfamily H (eag-related), member 2 Entrez:3757  HPRD: 01069  HGNC: 6251  Ensembl: ENSG00000055118 
KCNIP2Kv channel interacting protein 2 Entrez:30819  HGNC: 15522  Ensembl: ENSG00000120049  HPRD: 06880 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA1Bcalcium channel, voltage-dependent, N type, alpha 1B subunit
KCNH2potassium voltage-gated channel, subfamily H (eag-related), member 2
KCNIP2Kv channel interacting protein 2
Query geneGeneGene descriptionEdge score
GNAO1GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
CACNA1GCACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA1BCACNA1Bcalcium channel, voltage-dependent, N type, alpha 1B subunit
KCNH2KCNH2potassium voltage-gated channel, subfamily H (eag-related), member 2
KCNIP2KCNIP2Kv channel interacting protein 2

Troyanskaya Laboratory - Princeton University