ASD

GO:0030330 DNA damage response, signal transduction by p53 class mediator (88)

GeneInput weightStandardRank
PSMA1--42
PSMB3--79
PSMA4--95
PSMD14--120
PSMD8--144
PSMA5--219
PSMB1--318
PSMA3--373
PSMC4--380
PSMC6--405
PSMB7--554
PSMB4--562
SOX4--581
PSMD2--595
PPP2R5C--681
PSMB6--696
PSMA7--782
PSMC3--794
PSMC5--831
PSMD1--867
PSMD6--884
PSMC1--904
PSMD3--909
PSMD11--943
PSMC2--952
PSMD13--994
CDKN1B--1067
PSMD4--1166
EP300--11256
BAG6--1435
PSMA6--1492
PSME4--1576
PSMA2--1693
PSMD10--2012
PSMD12--2120
MSH2--12299
HIPK2--2306
PSMD7--2386
GML--2793
FOXO3--2950
DYRK2--3180
KAT5--4613
CDKN1A--4620
PAXIP1--5292
MDM2--5588
UBC--5781
TFAP4--6483
BCL3--6552
PCBP4--6619
PSME2--7488
PSMB9--7654
PSMB2--7801
PSMA8--8114
CDIP1--8126
MYO6--110509
ATM--110590
PSME1--11612
RFWD2--12054
PSMB8--12378
RBM38--12396
PSMD9--13761
BBC3--14408
PSMB11--14440
PSMB10--14502
TP73--15964
IFI16--16066
PSME3--17451
USP10--17654
PSMD5--18391
USP28--21173
AEN--21486
NBN--121778
TP530.25121968
UBB--22223
SP100--22701
RPS27A--22920
PSMF1--22952
TRIAP1--23071
ING4--23697
CDK2--24011
TP63--124113
UBA52--24116
BRCA1--124158
PSMB5--24489
GTSE1--24676
RPS27L--24874
PHLDA3--25021
PML--25248

Network

GO:0030330

Network
Enrichment
NameDescriptionExternal IDs
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1 Entrez:5682  Ensembl: ENSG00000129084  HPRD: 04170  HGNC: 9530 
PSMB3proteasome (prosome, macropain) subunit, beta type, 3 Entrez:5691  HPRD: 03709  Ensembl: ENSG00000108294  HGNC: 9540 
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4 Entrez:5685  Ensembl: ENSG00000041357  HPRD: 10168  HGNC: 9533 
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 Entrez:10213  HGNC: 16889  Ensembl: ENSG00000115233  HPRD: 06208 
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 Entrez:5714  Ensembl: ENSG00000099341  HPRD: 10171  HGNC: 9566 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMB3proteasome (prosome, macropain) subunit, beta type, 3
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
Query geneGeneGene descriptionEdge score
PSMA1PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMB3PSMB3proteasome (prosome, macropain) subunit, beta type, 3
PSMA4PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
PSMD14PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD8PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8

Troyanskaya Laboratory - Princeton University