ASD

GO:0031400 negative regulation of protein modification process (168)

GeneInput weightStandardRank
PPP2CA--21
SET--38
PSMA1--42
YWHAB0.25145
PSMB3--79
PSMA4--95
PSMD14--120
PSMD8--144
SFRP1--204
PSMA5--219
PSMB1--318
PSMA3--373
PSMC4--380
SNCA--1401
PSMC6--405
PSMB7--554
PSMB4--562
SOX4--581
SLIT2--582
PSMD2--595
PARK20.251634
JUN--647
PSMB6--696
YWHAE--772
LRP6--778
PSMA7--782
PSMC3--794
PSMC5--831
PPP2R1A--852
PSMD1--867
PSMD6--884
PSMC1--904
PSMD3--909
PSMD11--943
PSMC2--952
PSMD13--994
CTBP1--1017
PRKCZ--1110
PSMD4--1166
PRKCG--11280
SMAD7--1283
PSMA6--1492
JARID2--1504
SMAD3--1541
BUB3--1593
PSMA2--1693
TSC10.2511844
DUSP6--1889
PSMD10--2012
SMAD6--2079
PSMD12--2120
PTEN1.012260
PSMD7--2386
BCOR--12451
UBE2B--2708
PPP2R4--2768
PRNP--12842
INPP5J--2851
BAG5--2959
CDK50.2513113
WNT1--3263
MAS1--3300
USP44--3386
MGEA5--3440
LIMK1--3487
N4BP1--3558
MET1.013618
TNFAIP3--3628
SFRP2--3758
PAX5--3863
FZR1--3987
SKI--4231
NF2--14798
ADIPOQ0.2514834
RASD2--5271
ENPP1--15674
UBC--5781
HHATL--5786
PRKCD--5824
IL2--5825
G6PD--5896
DNMT1--5985
TWIST1--16128
FOXP3--16270
PPEF2--6387
UBE2E1--6513
MEN1--16723
DKK1--6892
DNAJB2--7177
ERRFI1--7414
PSME2--7488
ARRB2--7639
PSMB9--7654
PSMB2--7801
AKAP1--8358
ANAPC2--8902
CDC23--9012
VPS28--9081
CDKN2A--19650
SOCS1--9996
ATG5--10016
BDKRB2--10260
MLXIPL--10379
PPAP2B--10712
INSR--110986
TAF7--11048
ANAPC10--11143
PEBP1--11226
MAD2L2--11317
SAMSN1--11381
PSME1--11612
BDKRB1--11977
HNF4A--112281
PSMB8--12378
FAM129A--13472
GCLC--13506
ANAPC11--13665
PSMD9--13761
IGFBP3--13922
PSMB10--14502
TGFB10.25114736
USP4--14910
CDC27--14913
DNMT3B--16091
CNKSR3--16330
NLRP12--16984
PSME3--17451
ENG--117647
PSMD5--18391
ARRB1--19005
DVL1P1--19166
PSEN1--20241
CDC26--21067
PSEN2--21431
IRF1--121687
UBB--22223
ACER2--22351
UBXN1--22532
WWTR1--22777
MAD2L1--22813
RPS27A--22920
PSMF1--22952
IBTK--23069
UBE2D1--23789
IMPACT--23864
PTPN6--23968
TINF2--24064
UBA52--24116
BRCA1--124158
GTPBP4--24260
TRIM21--24431
PSMB5--24489
INPP5K--24643
CCNB1--24648
CAV1--124767
ANAPC7--24876
UFL1--24888
CDC20--24914
ANAPC5--24931
ANAPC4--25215
PML--25248
UBE2C--25279
CDC16--25415
FBXO5--25430
ANAPC1--25548
IGBP1--25575
BUB1B--125795
DNAJC10--25801

Network

GO:0031400

Network
Enrichment
NameDescriptionExternal IDs
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme Entrez:5515  HGNC: 9299  HPRD: 08912 
SETSET nuclear oncogene Entrez:6418  HGNC: 10760  HPRD: 09023  Ensembl: ENSG00000119335 
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1 Entrez:5682  Ensembl: ENSG00000129084  HPRD: 04170  HGNC: 9530 
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Entrez:7529  HGNC: 12849  Ensembl: ENSG00000166913  HPRD: 03184 
PSMB3proteasome (prosome, macropain) subunit, beta type, 3 Entrez:5691  HPRD: 03709  Ensembl: ENSG00000108294  HGNC: 9540 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
SETSET nuclear oncogene
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
PSMB3proteasome (prosome, macropain) subunit, beta type, 3
Query geneGeneGene descriptionEdge score
PPP2CAPPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
SETSETSET nuclear oncogene
PSMA1PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
YWHABYWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
PSMB3PSMB3proteasome (prosome, macropain) subunit, beta type, 3

Troyanskaya Laboratory - Princeton University