ASD

GO:0048663 neuron fate commitment (45)

GeneInput weightStandardRank
NTRK30.2514
ASCL1--229
POU4F1--292
PAX60.251355
OLIG2--420
NKX2-2--771
CDC42--1083
DLX20.2511235
ISL1--1441
ID2--1719
FOXA2--1835
JAG2--1852
PAX7--12033
FOXA1--2277
DLX10.2512366
NKX2-1--2488
WNT8B--2506
HOXD10--2845
SMAD4--2927
GSX1--2967
LHX6--2989
NKX6-1--3174
WNT1--3263
NOTCH1--13360
HES5--4001
HOXC10--4404
IHH--14742
BMP4--15180
LBX1--5371
NKX6-2--5422
TLX3--5583
HES10.2515662
GLI2--15731
SMO0.2515864
MNX1--5932
TGFBR1--16027
GSX2--6242
PTF1A--6703
GLI3--19032
ATOH1--9258
FOXA3--9582
AXIN1--110905
EVX1--12405
SHH--115942
NOTCH3--22751

Network

GO:0048663

Network
Enrichment
NameDescriptionExternal IDs
NTRK3neurotrophic tyrosine kinase, receptor, type 3 Entrez:4916  Ensembl: ENSG00000140538  HPRD: 01870  HGNC: 8033 
ASCL1achaete-scute complex homolog 1 (Drosophila) Entrez:429  HPRD: 00011  Ensembl: ENSG00000139352  HGNC: 738 
POU4F1POU class 4 homeobox 1 Entrez:5457  Ensembl: ENSG00000152192  HGNC: 9218  HPRD: 03379 
PAX6paired box 6 Entrez:5080  HPRD: 06167  Ensembl: ENSG00000007372  HGNC: 8620 
OLIG2oligodendrocyte lineage transcription factor 2 Entrez:10215  HPRD: 07334  Ensembl: ENSG00000205927  HGNC: 9398 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NTRK3neurotrophic tyrosine kinase, receptor, type 3
ASCL1achaete-scute complex homolog 1 (Drosophila)
POU4F1POU class 4 homeobox 1
PAX6paired box 6
OLIG2oligodendrocyte lineage transcription factor 2
Query geneGeneGene descriptionEdge score
NTRK3NTRK3neurotrophic tyrosine kinase, receptor, type 3
ASCL1ASCL1achaete-scute complex homolog 1 (Drosophila)
POU4F1POU4F1POU class 4 homeobox 1
PAX6PAX6paired box 6
OLIG2OLIG2oligodendrocyte lineage transcription factor 2

Troyanskaya Laboratory - Princeton University