ASD

GO:0031290 retinal ganglion cell axon guidance (14)

GeneInput weightStandardRank
SLIT1--33
EPHB1--152
SEMA4F--179
POU4F2--535
SLIT2--582
EPHA7--914
ROBO2--11224
ISL1--1441
ZIC2--11550
EPHB3--1893
BMPR1B--12397
PTPRM--3512
EFNA5--4967
POU4F3--16147

Network

GO:0031290

Network
Enrichment
NameDescriptionExternal IDs
SLIT1slit homolog 1 (Drosophila) Entrez:6585  Ensembl: ENSG00000187122  HGNC: 11085  HPRD: 04773 
EPHB1EPH receptor B1 Entrez:2047  HPRD: 02790  HGNC: 3392  Ensembl: ENSG00000154928 
SEMA4Fsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F Entrez:10505  HGNC: 10734  HPRD: 04748 
POU4F2POU class 4 homeobox 2 Entrez:5458  Ensembl: ENSG00000151615  HGNC: 9219  HPRD: 00220 
SLIT2slit homolog 2 (Drosophila) Entrez:9353  Ensembl: ENSG00000145147  HPRD: 04776  HGNC: 11086 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SLIT1slit homolog 1 (Drosophila)
EPHB1EPH receptor B1
SEMA4Fsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
POU4F2POU class 4 homeobox 2
SLIT2slit homolog 2 (Drosophila)
Query geneGeneGene descriptionEdge score
SLIT1SLIT1slit homolog 1 (Drosophila)
EPHB1EPHB1EPH receptor B1
SEMA4FSEMA4Fsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
POU4F2POU4F2POU class 4 homeobox 2
SLIT2SLIT2slit homolog 2 (Drosophila)

Troyanskaya Laboratory - Princeton University