ASD

GO:0016079 synaptic vesicle exocytosis (23)

GeneInput weightStandardRank
SYT1--5
SNAP250.2516
VAMP2--57
PCLO--114
SYNJ1--178
NLGN10.251265
STX1A0.251449
RAB3A0.251520
RIMS1--622
CPLX20.251956
SNPH--1251
SPTBN2--11344
UNC13A--1521
DOC2A0.2511649
SEPT5--1818
CPLX1--2921
OTOF--13204
CPLX3--3906
UNC13B--12427
STX4--13426
PSEN1--20241
SNAPIN--22880
BLOC1S6--23642

Network

GO:0016079

Network
Enrichment
NameDescriptionExternal IDs
SYT1synaptotagmin I Entrez:6857  HPRD: 01710  HGNC: 11509  Ensembl: ENSG00000067715 
SNAP25synaptosomal-associated protein, 25kDa Entrez:6616  Ensembl: ENSG00000132639  HPRD: 02637  HGNC: 11132 
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2) Entrez:6844  HGNC: 12643  HPRD: 01717  Ensembl: ENSG00000220205 
PCLOpiccolo presynaptic cytomatrix protein Entrez:27445  HPRD: 16078  HGNC: 13406  Ensembl: ENSG00000186472 
SYNJ1synaptojanin 1 Entrez:8867  Ensembl: ENSG00000159082  HGNC: 11503  HPRD: 09182 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SYT1synaptotagmin I
SNAP25synaptosomal-associated protein, 25kDa
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)
PCLOpiccolo presynaptic cytomatrix protein
SYNJ1synaptojanin 1
Query geneGeneGene descriptionEdge score
SYT1SYT1synaptotagmin I
SNAP25SNAP25synaptosomal-associated protein, 25kDa
VAMP2VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)
PCLOPCLOpiccolo presynaptic cytomatrix protein
SYNJ1SYNJ1synaptojanin 1

Troyanskaya Laboratory - Princeton University