ASD

GO:0030168 platelet activation (241)

GeneInput weightStandardRank
ATP2B20.511
GNB1--15
PFN1--74
KCNMA10.25187
ATP2B1--115
PRKCE--156
ATP2B3--190
CALM3--195
SLC8A2--232
YWHAZ0.251282
AKT10.251303
ACTN2--1376
GNAQ--490
GUCY1B3--560
KCNMB2--612
PRKCA--613
TGFB2--625
STXBP1--659
CALM1--708
DGKZ--725
SCG3--728
PDE10A--753
ALDOA0.251787
ITPR1--1802
DGKI--807
CX3CL1--832
ATP2A2--1881
PRKCB0.251889
NOS10.251908
TRPC3--971
RHOA--973
FLNA--1984
MAPK1--985
CAP1--1037
PIK3R10.2511065
RAC1--1087
PRKG1--1091
PRKCZ--1110
DGKB--1122
PRKCG--11280
FYN--1284
ACTN4--11332
SLC8A1--1339
GNAI3--1340
PDE2A--1591
GNAI1--1613
KCNMB4--1626
GUCY1A2--1629
PIK3R3--1659
DGKG--1661
TYRO3--1663
PDE1A--1704
WDR1--1708
GUCY1A3--1730
PDE1B--1791
TRPC7--1822
HRG--1850
TRPC6--11908
APP--1991
IGF10.2511993
CFL1--1997
ACTN1--2090
PDE11A--2107
LRP8--2215
SRC--2241
TIMP1--2285
GP5--2287
GNAS--12352
CALM2--2360
THPO--12471
PPIA--2548
RHOB--2589
RHOG--2753
PIK3CA0.2512782
VAV2--2783
HABP4--2882
RASGRP10.2512942
PDE3A--3024
PDE3B--3088
GNA11--3167
ALB--3224
SOD1--13330
TF--13351
GNG2--3365
GNA14--3434
TUBA4A--3456
SLC8A3--3637
P2RY12--3680
PRKG2--3702
BRPF3--3819
VAV3--4024
ATP2B4--4085
PDPK1--4150
HGF0.2514189
TMSB4X--4291
ITGB30.514442
P2RY1--4483
F2RL2--4517
IL6--14578
DAGLA--4670
PDGFA--4678
VEGFA0.2514691
CD63--4699
MAPK14--4729
PDE9A--4793
MRVI1--4813
PLG--4815
WNT3A--4844
DGKE--4906
MPL--14908
FGB--14982
PSAP--4990
KNG1--5045
FIGF--5086
VEGFC--5203
FGA--15235
LYN--5289
TGFB3--15321
LEFTY2--5386
PIK3R2--5501
RAF10.2515559
PRKCD--5824
PDE6A--5844
MAPK30.2516096
DGKD--6199
GNAI2--6384
SRGN--6476
F5--16573
GP6--6821
KCNMB3--6842
CD40LG--6844
MERTK--6860
NOS20.2517024
IL11--7322
TTN--17396
F2RL3--7474
ARRB2--7639
ADAMTS13--7686
MMRN1--8086
KCNMB1--8171
APOB--8237
PDE5A--8315
ITPR2--8681
ENTPD2--8725
PIK3CG0.2518744
EGF0.2518839
PRKCH--19574
GP9--19594
TREML1--9603
DGKH--9885
MGLL--10038
PPBP--10059
PIK3CB--10067
PTPN11--110178
SELP--10263
F2--110327
PDE6B--110483
STXBP3--10747
TLN1--10867
GNA12--10962
APOA1--111900
GP1BB--112211
RASGRP2--12257
PF4--12421
PDGFB--12484
F2R--12498
F13A1--112507
SERPINF2--12582
ORAI1--12675
NOS3--12710
F8--12711
DGKQ--12728
GUCY1B2--13097
FGG--13182
PIK3R6--13382
STX4--13426
VWF--113589
FERMT3--113621
HSPA5--13639
BLOC1S3--13724
RAC2--14121
COL3A1--114131
PRKCQ--14566
PLSCR1--14718
TGFB10.25114736
TBXA2R--15453
STIM1--15530
PIK3R5--15566
POTEKP--15762
ITGA2B--116376
DGKK--16510
PTGIR0.25117719
FCER1G--17885
PLA2G4A--18503
ARRB1--19005
DAGLB--19100
COL1A2--119210
FZD6--19825
PDE6G--119831
VEGFB--20069
FGR--20122
GNA15--20239
GNA13--20348
P2RX1--20551
VCL--120649
SERPINE10.25120720
LCP2--20827
ATP2A1--121263
GATA1--121632
AXL--21695
SAA1--21772
THBS1--21993
ATP2A3--22022
FN1--22085
GP1BA--122153
CD9--22311
ITPR3--22312
PLEK--22429
LAT--22661
CD36--22749
ABCC4--22851
SAA2--22914
VAV1--23026
CFD--23288
DGKA--23509
PECAM10.25123527
A2M--23790
SYK--23795
SERPING1--123797
CALU--23966
PTPN6--23968
SERPINA1--124081
SPARC--24433
COL1A1--124560
PLCG2--24804
CLU--24939
LCK--24966
CD40--25086
GAS6--25087
LAMP2--125516
PROS1--25567

Network

GO:0030168

Network
Enrichment
NameDescriptionExternal IDs
ATP2B2ATPase, Ca++ transporting, plasma membrane 2 Entrez:491  HGNC: 815  Ensembl: ENSG00000157087  HPRD: 00160 
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1 Entrez:2782  HGNC: 4396  HPRD: 00766  Ensembl: ENSG00000078369 
PFN1profilin 1 Entrez:5216  Ensembl: ENSG00000108518  HGNC: 8881  HPRD: 01452 
KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1 Entrez:3778  Ensembl: ENSG00000156113  HGNC: 6284  HPRD: 15967 
ATP2B1ATPase, Ca++ transporting, plasma membrane 1 Entrez:490  Ensembl: ENSG00000070961  HGNC: 814  HPRD: 00158 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ATP2B2ATPase, Ca++ transporting, plasma membrane 2
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
PFN1profilin 1
KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1
ATP2B1ATPase, Ca++ transporting, plasma membrane 1
Query geneGeneGene descriptionEdge score
ATP2B2ATP2B2ATPase, Ca++ transporting, plasma membrane 2
GNB1GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
PFN1PFN1profilin 1
KCNMA1KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1
ATP2B1ATP2B1ATPase, Ca++ transporting, plasma membrane 1

Troyanskaya Laboratory - Princeton University