ASD

GO:0043523 regulation of neuron apoptosis (133)

GeneInput weightStandardRank
SET--38
ADNP0.5191
GRIK20.51142
UBE2M--148
GPI--1155
GABRA50.251157
GRIN1--167
ASCL1--229
CACNA1A--1231
CRHR1--280
POU4F1--292
CRH--328
NF10.251333
SNCA--1401
CDK5R1--406
SRPK2--412
NR3C1--463
NR4A3--1594
TGFB2--625
JUN--647
NR4A20.251713
PCSK6--731
BDNF0.251754
TOX3--755
GRIK5--890
EPHA7--914
ERBB3--921
RHOA--973
HRK--1059
GABRB2--1069
UBE2V2--1207
CNTFR--1219
SNCB--11222
ISL1--1441
TGFA--1563
TYRO3--1663
ITSN1--1679
PARK7--11831
CITED1--1867
AGAP2--1884
ESR10.2511914
PPARGC1A--1920
MUSK--2237
NTF30.2512294
MSH2--12299
HIPK2--2306
DLX10.2512366
BCL20.2512759
FASLG--12766
ILK--2917
SPECC1L--3048
CDK50.2513113
GRID20.2513322
SOD1--13330
NDNF--3722
NGF0.2513749
AGT--13783
RASA1--4166
FOXB1--4202
BARHL1--4409
GDNF--14462
IL6--14578
SIX4--4623
FURIN--4868
ROCK1--5154
CNTF--5263
TGFB3--15321
KCNIP3--5329
RILPL1--5358
BCL2L11--5454
ATP7A--15491
AGRN0.2515611
CRLF1--5774
GRM4--5804
GPX10.2516748
PTPRF--6764
BCL2L1--7198
GLP1R--7291
BAX--7313
PMAIP1--7387
PCSK9--8260
MAP2K7--8382
WFS10.2518575
KDM2B--8663
UCN--8987
ADORA2A0.2519605
RHOC--9929
GHR--110058
DHCR24--10169
PPT1--110364
ATM--110590
SOD2--12001
EPO--12314
F2R--12498
BRAF--112672
AKT1S1--12840
HRAS0.25112845
CASP2--12965
NMNAT3--13280
GCLC--13506
CLN3--113525
RAPSN--13568
ABCC1--13942
ITGA1--13957
SIX1--115117
LIG4--115324
TP73--15964
TNF0.25119823
VEGFB--20069
PSEN1--20241
HMOX1--20520
ADAM8--20729
PRDX3--20779
CCL5--21529
XRCC2--21673
AXL--21695
NCF2--121812
TP530.25121968
NRBP2--22016
CLCF1--22182
MDK--22267
AARS--22308
IL18--22799
NMNAT1--23017
MAP3K11--23341
LGMN--23802
CASP7--24086
TP63--124113
CASP6--24423
ALKBH1--24439
GCLM--24501
NQO1--24933
XRCC4--24940

Network

GO:0043523

Network
Enrichment
NameDescriptionExternal IDs
SETSET nuclear oncogene Entrez:6418  HGNC: 10760  HPRD: 09023  Ensembl: ENSG00000119335 
ADNPactivity-dependent neuroprotector homeobox Entrez:23394  Ensembl: ENSG00000101126  HPRD: 09793  HGNC: 15766 
GRIK2glutamate receptor, ionotropic, kainate 2 Entrez:2898  Ensembl: ENSG00000164418  HGNC: 4580  HPRD: 00692 
UBE2Mubiquitin-conjugating enzyme E2M Entrez:9040  HPRD: 04414  HGNC: 12491  Ensembl: ENSG00000130725 
GPIglucose-6-phosphate isomerase Entrez:2821  HPRD: 01394  HGNC: 4458  Ensembl: ENSG00000105220 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SETSET nuclear oncogene
ADNPactivity-dependent neuroprotector homeobox
GRIK2glutamate receptor, ionotropic, kainate 2
UBE2Mubiquitin-conjugating enzyme E2M
GPIglucose-6-phosphate isomerase
Query geneGeneGene descriptionEdge score
SETSETSET nuclear oncogene
ADNPADNPactivity-dependent neuroprotector homeobox
GRIK2GRIK2glutamate receptor, ionotropic, kainate 2
UBE2MUBE2Mubiquitin-conjugating enzyme E2M
GPIGPIglucose-6-phosphate isomerase

Troyanskaya Laboratory - Princeton University