ASD

GO:0051495 positive regulation of cytoskeleton organization (75)

GeneInput weightStandardRank
MAPT0.25131
PFN1--74
SFRP1--204
STMN2--221
MAP1B--300
PFN2--431
APC0.251528
TAC10.251543
ACTR3--573
ARPC2--578
AMOT--933
PROX1--962
RHOA--973
CDKN1B--1067
RAC1--1087
EP300--11256
SMAD3--1541
ARPC4--1795
LIMK1--3487
TERF1--3607
ARF6--4366
WNT11--4528
NCK2--4595
CLIP1--4720
NF2--14798
KATNB1--5389
ARL2--6405
P2RX7--6517
MAP3K1--16751
CCL11--7037
MLST8--7510
TACR1--7688
KISS1R--8159
DSTN--9088
PDXP--9557
EDN1--9566
RHOC--9929
NCK1--10453
DLG1--10557
CAV3--110580
SCIN--11105
NES--11295
CDC42EP5--12367
ARHGEF10--12556
MYLK3--12912
WASH2P--14471
SORBS3--14540
PRKCQ--14566
JMY--14571
F2RL1--15088
MTOR--15435
WASH6P--16214
CCL24--17974
WASH3P--18486
WASH4P--18575
CCL21--19130
TRPV4--119357
CDC42EP2--19516
CCL26--19975
GPR65--20238
WASH1--20505
CCR7--21314
VIL1--22201
ARHGEF10L--22238
SDC4--22313
PLEK--22429
NCKAP1L--23440
TPM1--123549
BAIAP2L1--24533
FHOD1--24644
CCNB1--24648
PSRC1--24661
CAV1--124767
SYNPO--24784
PLK4--25448

Network

GO:0051495

Network
Enrichment
NameDescriptionExternal IDs
MAPTmicrotubule-associated protein tau Entrez:4137  HGNC: 6893  Ensembl: ENSG00000186868  HPRD: 01142 
PFN1profilin 1 Entrez:5216  Ensembl: ENSG00000108518  HGNC: 8881  HPRD: 01452 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
STMN2stathmin-like 2 Entrez:11075  HGNC: 10577  HPRD: 09003  Ensembl: ENSG00000104435 
MAP1Bmicrotubule-associated protein 1B Entrez:4131  HPRD: 01139  HGNC: 6836  Ensembl: ENSG00000131711 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MAPTmicrotubule-associated protein tau
PFN1profilin 1
SFRP1secreted frizzled-related protein 1
STMN2stathmin-like 2
MAP1Bmicrotubule-associated protein 1B
Query geneGeneGene descriptionEdge score
MAPTMAPTmicrotubule-associated protein tau
PFN1PFN1profilin 1
SFRP1SFRP1secreted frizzled-related protein 1
STMN2STMN2stathmin-like 2
MAP1BMAP1Bmicrotubule-associated protein 1B

Troyanskaya Laboratory - Princeton University