ASD

GO:0046823 negative regulation of nucleocytoplasmic transport (38)

GeneInput weightStandardRank
NF10.251333
SOX4--581
G3BP2--608
APC2--671
TXN--803
PKIA--959
BMP7--987
FBXW11--1610
PSMD10--2012
MXI1--12895
CDK50.2513113
DAB2IP--3635
NLRP30.2514091
BARD1--14151
MAPK7--4626
CYLD--15851
AXIN2--15927
NFKBIA--6067
KEAP1--6336
IL10--17883
AKAP1--8358
SFRP5--9913
MDFI--11799
UACA--12262
TACC3--13022
NFKBIE--14547
MDFIC--14627
MTOR--15435
PKIG--20074
TONSL--20185
NFKBIL1--21296
FZD1--22086
NFKBIB--22383
CD36--22749
WWTR1--22777
SNAI2--122934
FAF1--24152
EMD--124154

Network

GO:0046823

Network
Enrichment
NameDescriptionExternal IDs
NF1neurofibromin 1 Entrez:4763  HGNC: 7765  HPRD: 01203  Ensembl: ENSG00000196712 
SOX4SRY (sex determining region Y)-box 4 Entrez:6659  HPRD: 01695  HGNC: 11200  Ensembl: ENSG00000124766 
G3BP2GTPase activating protein (SH3 domain) binding protein 2 Entrez:9908  HPRD: 06570  HGNC: 30291  Ensembl: ENSG00000138757 
APC2adenomatosis polyposis coli 2 Entrez:10297  Ensembl: ENSG00000115266  HGNC: 24036  HPRD: 09802 
TXNthioredoxin Entrez:7295  HGNC: 12435  Ensembl: ENSG00000136810  HPRD: 01761 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NF1neurofibromin 1
SOX4SRY (sex determining region Y)-box 4
G3BP2GTPase activating protein (SH3 domain) binding protein 2
APC2adenomatosis polyposis coli 2
TXNthioredoxin
Query geneGeneGene descriptionEdge score
NF1NF1neurofibromin 1
SOX4SOX4SRY (sex determining region Y)-box 4
G3BP2G3BP2GTPase activating protein (SH3 domain) binding protein 2
APC2APC2adenomatosis polyposis coli 2
TXNTXNthioredoxin

Troyanskaya Laboratory - Princeton University