ASD

GO:0042430 indole-containing compound metabolic process (24)

GeneInput weightStandardRank
ATP2B20.511
GRIN2A0.25156
PDE1B--1791
CCBL1--2244
ASMTL--2741
CYP19A10.2513314
SRD5A10.2513730
TPH20.2514182
ACMSD--4861
DDC0.2515222
ATP7A--15491
ASMT0.2515574
IDO2--5792
TPH10.2516110
AANAT0.2516439
TDO20.2517100
KMO--9843
HAAO--12460
KYNU--12935
AFMID--13136
MAOA0.25113422
AADAT--13782
IDO1--20843
CCBL2--22553

Network

GO:0042430

Network
Enrichment
NameDescriptionExternal IDs
ATP2B2ATPase, Ca++ transporting, plasma membrane 2 Entrez:491  HGNC: 815  Ensembl: ENSG00000157087  HPRD: 00160 
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
PDE1Bphosphodiesterase 1B, calmodulin-dependent Entrez:5153  HGNC: 8775  Ensembl: ENSG00000123360  HPRD: 01388 
CCBL1cysteine conjugate-beta lyase, cytoplasmic Entrez:883  HPRD: 02769  Ensembl: ENSG00000171097  HGNC: 1564 
ASMTLacetylserotonin O-methyltransferase-like Entrez:8623  HGNC: 751  Ensembl: ENSG00000169093  HPRD: 02156 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ATP2B2ATPase, Ca++ transporting, plasma membrane 2
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
PDE1Bphosphodiesterase 1B, calmodulin-dependent
CCBL1cysteine conjugate-beta lyase, cytoplasmic
ASMTLacetylserotonin O-methyltransferase-like
Query geneGeneGene descriptionEdge score
ATP2B2ATP2B2ATPase, Ca++ transporting, plasma membrane 2
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
PDE1BPDE1Bphosphodiesterase 1B, calmodulin-dependent
CCBL1CCBL1cysteine conjugate-beta lyase, cytoplasmic
ASMTLASMTLacetylserotonin O-methyltransferase-like

Troyanskaya Laboratory - Princeton University