ASD

GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity (133)

GeneInput weightStandardRank
NEUROD2--68
NEUROD1--1136
KRAS--1143
CAMK2A--183
AKT10.251303
EDA--1615
UBE2N--693
SMARCA4--751
NKX2-2--771
LRP6--778
ERC1--902
HDAC4--963
WNT10B--1030
NCOA3--1178
EP300--11256
RELA--1352
EPHA5--1409
PSMA6--1492
AR0.2511499
ZIC2--11550
FZD4--11666
WNT20.2511783
PPARGC1A--1920
PPP2R5B--2024
UBE2I--2101
MAP3K7--2169
PTEN1.012260
FOXA1--2277
TERF2IP--2316
NEUROG2--2345
MTDH--2631
HDAC5--2683
ARHGEF2--2743
TAB2--2777
MAP3K13--2868
WNT5A--2870
ARID5B--3070
NKX6-1--3174
WNT1--3263
NEUROG10.2513515
NGF0.2513749
AGT--13783
PLA2G1B--4440
IL6--14578
EDA2R--4611
TNFRSF11A--14672
IL4--4723
TSSK4--5561
UBC--5781
SMO0.2515864
TCF3--5880
CEBPG--6059
NFKBIA--6067
IL1B--16220
TAB3--6412
TP53BP1--6777
ABRA--6916
IL5--7116
TLR4--17283
NEUROG3--7305
TNFSF11--17511
IL10--17883
DDR2--8276
TGFBR3--8717
IRAK1--9309
RHEBL1--9555
CDKN2A--19650
TAB1--9783
AMH--10166
PPAP2B--10712
NPM1--110878
IRAK2--11461
CHUK--11526
HMGN3--11816
GTF2A2--11944
DVL2--12293
TRIM320.25112319
TLR9--12436
UBE2V1--12516
JUP--112627
TLR2--112838
SMARCB1--112909
TNFRSF8--13160
RIPK2--13928
FZD2--13981
IRAK3--14013
ICAM1--14063
JMY--14571
TGFB10.25114736
MALT1--14761
TRAF6--14847
SHH--115942
KDM1A--15967
PYCARD--16138
TRAF1--17325
MYD88--17730
INS--119021
TNF0.25119823
NFKB1--20216
TLR3--20315
RNF25--20457
ADAM8--20729
PRDX3--20779
ANXA3--20797
TRAF5--20940
RNF31--21239
NFKB2--21498
TICAM1--21522
SPHK1--21548
IKBKB--21674
TIRAP--21732
PPARG--121945
FZD1--22086
STK36--22089
UBB--22223
NFAM1--22287
NFKBIB--22383
DDX58--22541
NOD2--122677
SP100--22701
AGER--22826
RPS27A--22920
RIPK1--23173
RBCK1--23437
TRAF2--23633
CARD11--23657
NOD1--23711
IKBKG--123817
UBA52--24116
BCL10--124165
CLU--24939
CAT--25336
MAVS--25347

Network

GO:0051091

Network
Enrichment
NameDescriptionExternal IDs
NEUROD2neuronal differentiation 2 Entrez:4761  HPRD: 03429  HGNC: 7763 
NEUROD1neuronal differentiation 1 Entrez:4760  HPRD: 03428  HGNC: 7762  Ensembl: ENSG00000162992 
KRASKirsten rat sarcoma viral oncogene homolog Entrez:3845  Ensembl: ENSG00000133703  HGNC: 6407  HPRD: 01817 
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha Entrez:815  HGNC: 1460  HPRD: 06532  Ensembl: ENSG00000070808 
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NEUROD2neuronal differentiation 2
NEUROD1neuronal differentiation 1
KRASKirsten rat sarcoma viral oncogene homolog
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha
AKT1v-akt murine thymoma viral oncogene homolog 1
Query geneGeneGene descriptionEdge score
NEUROD2NEUROD2neuronal differentiation 2
NEUROD1NEUROD1neuronal differentiation 1
KRASKRASKirsten rat sarcoma viral oncogene homolog
CAMK2ACAMK2Acalcium/calmodulin-dependent protein kinase II alpha
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1

Troyanskaya Laboratory - Princeton University