ASD

GO:0043491 protein kinase B signaling cascade (13)

GeneInput weightStandardRank
PAX2--459
EP300--11256
TYRO3--1663
PIK3CA0.2512782
AKT2--13025
P2RY12--3680
LINGO1--6233
MERTK--6860
PIK3C2B--7094
TSC20.25111448
EPHA2--114150
AXL--21695
GAS6--25087

Network

GO:0043491

Network
Enrichment
NameDescriptionExternal IDs
PAX2paired box 2 Entrez:5076  HGNC: 8616  Ensembl: ENSG00000075891  HPRD: 01330 
EP300E1A binding protein p300 Entrez:2033  Ensembl: ENSG00000100393  HGNC: 3373  HPRD: 04078 
TYRO3TYRO3 protein tyrosine kinase Entrez:7301  Ensembl: ENSG00000092445  HGNC: 12446  HPRD: 02641 
PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha Entrez:5290  HGNC: 8975  HPRD: 01382 
AKT2v-akt murine thymoma viral oncogene homolog 2 Entrez:208  HPRD: 01262  Ensembl: ENSG00000105221  HGNC: 392 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PAX2paired box 2
EP300E1A binding protein p300
TYRO3TYRO3 protein tyrosine kinase
PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
AKT2v-akt murine thymoma viral oncogene homolog 2
Query geneGeneGene descriptionEdge score
PAX2PAX2paired box 2
EP300EP300E1A binding protein p300
TYRO3TYRO3TYRO3 protein tyrosine kinase
PIK3CAPIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
AKT2AKT2v-akt murine thymoma viral oncogene homolog 2

Troyanskaya Laboratory - Princeton University