ASD

GO:0050810 regulation of steroid biosynthetic process (41)

GeneInput weightStandardRank
NR3C1--463
IGF1R--631
PROX1--962
FGF1--1005
TSPO0.2511277
INSIG1--1440
POR0.2512359
LHCGR0.2512362
CYP17A10.2513171
BMP6--3242
SOD1--13330
DKK3--4056
SCAP--4068
ATP1A10.2514084
SF1--4401
IL1A--4552
IFNG--15255
HRH1--5298
STAR--5840
CYP7A10.2516478
DHH--16915
NR5A1--17588
GFI1--17699
SNAI1--8474
FGF19--10321
ADORA2B--11164
SEC14L2--11778
INSIG2--12416
REST--13067
LEP0.25113368
SREBF1--16874
ABCG1--17188
TNF0.25119823
NFKB1--20216
APOE0.25121310
WNT4--21840
PEX2--122416
DHCR70.25122787
SNAI2--122934
IGF20.25123391
PRKAA1--24385

Network

GO:0050810

Network
Enrichment
NameDescriptionExternal IDs
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Entrez:2908  HPRD: 00679  HGNC: 7978  Ensembl: ENSG00000113580 
IGF1Rinsulin-like growth factor 1 receptor Entrez:3480  Ensembl: ENSG00000140443  HPRD: 00932  HGNC: 5465 
PROX1prospero homeobox 1 Entrez:5629  HPRD: 03330  HGNC: 9459  Ensembl: ENSG00000117707 
FGF1fibroblast growth factor 1 (acidic) Entrez:2246  HGNC: 3665  Ensembl: ENSG00000113578  HPRD: 00567 
TSPOtranslocator protein (18kDa) Entrez:706  Ensembl: ENSG00000100300  HGNC: 1158  HPRD: 15913 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
IGF1Rinsulin-like growth factor 1 receptor
PROX1prospero homeobox 1
FGF1fibroblast growth factor 1 (acidic)
TSPOtranslocator protein (18kDa)
Query geneGeneGene descriptionEdge score
NR3C1NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
IGF1RIGF1Rinsulin-like growth factor 1 receptor
PROX1PROX1prospero homeobox 1
FGF1FGF1fibroblast growth factor 1 (acidic)
TSPOTSPOtranslocator protein (18kDa)

Troyanskaya Laboratory - Princeton University