ASD

GO:0071902 positive regulation of protein serine/threonine kinase activity (176)

GeneInput weightStandardRank
PPP2CA--21
HTR2A0.25151
KRAS--1143
AKT10.251303
SNCA--1401
CDK5R1--406
MAP2K10.251474
MAP3K9--500
GRM10.251523
GNG3--591
CCND2--689
PDCD10--883
MADD--898
PROX1--962
MAPK1--985
MAP2K20.2511066
MAP3K5--1245
MAPK11--1258
SPAG9--1398
EDN3--11522
SPRY2--1552
ADRA2A0.2511556
TGFA--1563
CHRNA70.511657
MAP3K10--1767
CD81--11828
GAB1--1864
PKN1--1964
PSMD10--2012
MAP3K7--2169
ZFP91--2271
MAPK8IP3--2496
FZD10--2606
TAB2--2777
EGFR--12811
WNT5A--2870
ILK--2917
NOX4--2930
LPAR1--2975
PTK2B--3191
PDE6H--3301
SOD1--13330
MAPKAPK2--3441
MET1.013618
DAB2IP--3635
PROK2--13667
CXCR4--4014
HGF0.2514189
FGF10--14373
DVL3--4438
PLA2G1B--4440
GH1--4570
ZEB2--4607
TNFRSF11A--14672
PDGFA--4678
VEGFA0.2514691
MAPK14--4729
ADIPOQ0.2514834
MAP4K5--4887
DUSP19--5073
HTR2B--5233
CCND1--15288
TGFB3--15321
PAK1--5556
UBC--5781
GRM4--5804
SHC1--5839
STK4--6010
MAPK30.2516096
TNFSF15--6158
IL1B--16220
WNT7A--6375
TAB3--6412
ADRA2C--6524
MAP3K4--6590
MAP3K1--16751
TDGF1--6833
DRD40.2517058
TLR4--17283
C1QTNF2--7354
PLCE1--7692
WNT7B--7693
TLR6--7973
ADRA2B--8196
PROK1--8256
PIM1--8325
MAP2K7--8382
EGF0.2518839
PRDX2--8945
MAP2K3--9005
IRAK1--9309
GHRL0.2519333
EDN1--9566
FGF2--9627
DAXX--9639
TAB1--9783
MAP3K2--10013
GHR--110058
PIK3CB--10067
MAP2K6--10398
LPAR3--10488
AXIN1--110905
INSR--110986
ADAM17--11074
ADORA2B--11164
IRAK2--11461
EPGN--11496
FGD4--111677
ELANE--111717
MDFI--11799
CCL19--11890
CCND3--12093
BIRC7--12220
RPTOR--12241
DVL2--12293
ALS2--112325
TLR9--12436
PDGFB--12484
FRS2--12610
TNFRSF10B--12951
CD24--113608
CARD14--13915
RIPK2--13928
ITGA1--13957
IQGAP3--14020
FPR1--14197
DBNL--14433
LPAR2--14606
MDFIC--14627
CCNY--14714
TGFB10.25114736
MALT1--14761
TRAF6--14847
HSPA2--15307
C5--115436
TP73--15964
C5AR1--16349
S1PR2--18246
TNF0.25119823
PDE6G--119831
AJUBA--19840
TPD52L1--20081
PSEN1--20241
TLR3--20315
ADAM8--20729
MAP4K2--20924
PDGFRB--21054
TNFRSF10A--21606
ERBB2--121638
EFNA1--21813
THBS1--21993
UBB--22223
SLC27A1--22268
MAP4K1--22293
MUL1--22450
STK3--22605
CD74--22633
NOD2--122677
CARD10--22698
PTPLAD1--22865
RPS27A--22920
RIPK1--23173
MAP3K11--23341
AVPI1--23367
ACSL1--23377
IGF20.25123391
TRAF2--23633
MAPKAPK3--23643
NOD1--23711
SYK--23795
IKBKG--123817
CDK1--24001
UBA52--24116
PRKAA1--24385
MAP3K6--24401
IL1RN0.25124819

Network

GO:0071902

Network
Enrichment
NameDescriptionExternal IDs
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme Entrez:5515  HGNC: 9299  HPRD: 08912 
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Entrez:3356  HPRD: 01638  Ensembl: ENSG00000102468  HGNC: 5293 
KRASKirsten rat sarcoma viral oncogene homolog Entrez:3845  Ensembl: ENSG00000133703  HGNC: 6407  HPRD: 01817 
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
SNCAsynuclein, alpha (non A4 component of amyloid precursor) Entrez:6622  HPRD: 01227  HGNC: 11138  Ensembl: ENSG00000145335 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
KRASKirsten rat sarcoma viral oncogene homolog
AKT1v-akt murine thymoma viral oncogene homolog 1
SNCAsynuclein, alpha (non A4 component of amyloid precursor)
Query geneGeneGene descriptionEdge score
PPP2CAPPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
HTR2AHTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
KRASKRASKirsten rat sarcoma viral oncogene homolog
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1
SNCASNCAsynuclein, alpha (non A4 component of amyloid precursor)

Troyanskaya Laboratory - Princeton University