ASD

GO:0016574 histone ubiquitination (28)

GeneInput weightStandardRank
RYBP--135
WAC--565
UBE2N--693
USP22--1375
UBE2A0.2511473
SUZ12--1913
BMI1--2175
BCOR--12451
UBE2B--2708
CBX8--4367
HUWE1--4890
SKP1--6164
UBE2E1--6513
RNF8--6838
RNF40--7070
RNF2--8552
KDM2B--8663
RAG1--9821
PCGF1--11019
RNF168--11188
PAF1--11366
CDC73--112583
UBR2--13299
RING1--14496
DTX3L--14563
CTR9--15045
LEO1--19960
RNF20--22923

Network

GO:0016574

Network
Enrichment
NameDescriptionExternal IDs
RYBPRING1 and YY1 binding protein Entrez:23429  HGNC: 10480  HPRD: 09607 
WACWW domain containing adaptor with coiled-coil Entrez:51322  Ensembl: ENSG00000095787  HGNC: 17327  HPRD: 18291 
UBE2Nubiquitin-conjugating enzyme E2N Entrez:7334  HGNC: 12492  HPRD: 04725 
USP22ubiquitin specific peptidase 22 Entrez:23326  HGNC: 12621  Ensembl: ENSG00000124422 
UBE2Aubiquitin-conjugating enzyme E2A Entrez:7319  HPRD: 02422  HGNC: 12472  Ensembl: ENSG00000077721 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
RYBPRING1 and YY1 binding protein
WACWW domain containing adaptor with coiled-coil
UBE2Nubiquitin-conjugating enzyme E2N
USP22ubiquitin specific peptidase 22
UBE2Aubiquitin-conjugating enzyme E2A
Query geneGeneGene descriptionEdge score
RYBPRYBPRING1 and YY1 binding protein
WACWACWW domain containing adaptor with coiled-coil
UBE2NUBE2Nubiquitin-conjugating enzyme E2N
USP22USP22ubiquitin specific peptidase 22
UBE2AUBE2Aubiquitin-conjugating enzyme E2A

Troyanskaya Laboratory - Princeton University