ASD

GO:0048260 positive regulation of receptor-mediated endocytosis (21)

GeneInput weightStandardRank
SYNJ1--178
HNRNPK--746
BICD1--760
SGIP1--1331
HIP1--1990
DRD20.2512071
CBL--2611
ANGPT1--3376
SFRP4--3511
WNT3A--4844
PCSK9--8260
VTN--9385
PPT1--110364
SELE--10573
CCL19--11890
APOA5--113056
CCL21--19130
SERPINE10.25120720
PLD2--23098
SCYL2--24230
LDLRAP1--25301

Network

GO:0048260

Network
Enrichment
NameDescriptionExternal IDs
SYNJ1synaptojanin 1 Entrez:8867  Ensembl: ENSG00000159082  HGNC: 11503  HPRD: 09182 
HNRNPKheterogeneous nuclear ribonucleoprotein K Entrez:3190  HGNC: 5044  Ensembl: ENSG00000165119  HPRD: 02834 
BICD1bicaudal D homolog 1 (Drosophila) Entrez:636  Ensembl: ENSG00000151746  HGNC: 1049  HPRD: 03730 
SGIP1SH3-domain GRB2-like (endophilin) interacting protein 1 Entrez:84251  Ensembl: ENSG00000118473  HPRD: 10910  HGNC: 25412 
HIP1huntingtin interacting protein 1 Entrez:3092  HGNC: 4913  Ensembl: ENSG00000127946  HPRD: 03461 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SYNJ1synaptojanin 1
HNRNPKheterogeneous nuclear ribonucleoprotein K
BICD1bicaudal D homolog 1 (Drosophila)
SGIP1SH3-domain GRB2-like (endophilin) interacting protein 1
HIP1huntingtin interacting protein 1
Query geneGeneGene descriptionEdge score
SYNJ1SYNJ1synaptojanin 1
HNRNPKHNRNPKheterogeneous nuclear ribonucleoprotein K
BICD1BICD1bicaudal D homolog 1 (Drosophila)
SGIP1SGIP1SH3-domain GRB2-like (endophilin) interacting protein 1
HIP1HIP1huntingtin interacting protein 1

Troyanskaya Laboratory - Princeton University