ASD

GO:0001990 regulation of systemic arterial blood pressure by hormone (21)

GeneInput weightStandardRank
RPS6KA20.251711
NOX1--1232
AGTR20.2511418
EDN3--11522
NKX2-1--2488
DRD30.2512757
AGTR1--12898
CYBA--13439
AGT--13783
CORIN--3841
REN--16631
ACE--9212
EDN1--9566
ACE2--10229
HSD11B2--10731
CYP11B2--11354
PCSK5--12160
NOS3--12710
EDN2--13347
ECE1--120668
ATP6AP2--24552

Network

GO:0001990

Network
Enrichment
NameDescriptionExternal IDs
RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 2 Entrez:6196  Ensembl: ENSG00000071242  HPRD: 03403  HGNC: 10431 
NOX1NADPH oxidase 1 Entrez:27035  HGNC: 7889  Ensembl: ENSG00000007952  HPRD: 02203 
AGTR2angiotensin II receptor, type 2 Entrez:186  HPRD: 02071  HGNC: 338  Ensembl: ENSG00000180772 
EDN3endothelin 3 Entrez:1908  HGNC: 3178  Ensembl: ENSG00000124205  HPRD: 00570 
NKX2-1NK2 homeobox 1 Entrez:7080  HPRD: 02798  HGNC: 11825  Ensembl: ENSG00000136352 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 2
NOX1NADPH oxidase 1
AGTR2angiotensin II receptor, type 2
EDN3endothelin 3
NKX2-1NK2 homeobox 1
Query geneGeneGene descriptionEdge score
RPS6KA2RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 2
NOX1NOX1NADPH oxidase 1
AGTR2AGTR2angiotensin II receptor, type 2
EDN3EDN3endothelin 3
NKX2-1NKX2-1NK2 homeobox 1

Troyanskaya Laboratory - Princeton University