ASD

GO:0006182 cGMP biosynthetic process (15)

GeneInput weightStandardRank
HTR2C0.25146
GUCY1B3--560
GUCY1A2--1629
GUCY1A3--1730
GUCY2F--3945
GUCY2D--15204
HTR2B--5233
NPPB--5967
NPR2--16150
NPPC--7442
GUCY2C--8098
GUCA2B--8899
NPPA--110598
AQP1--21019
NPR1--24360

Network

GO:0006182

Network
Enrichment
NameDescriptionExternal IDs
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Entrez:3358  HGNC: 5295  HPRD: 02429  Ensembl: ENSG00000147246 
GUCY1B3guanylate cyclase 1, soluble, beta 3 Entrez:2983  HGNC: 4687  Ensembl: ENSG00000061918  HPRD: 00769 
GUCY1A2guanylate cyclase 1, soluble, alpha 2 Entrez:2977  Ensembl: ENSG00000152402  HGNC: 4684  HPRD: 03146 
GUCY1A3guanylate cyclase 1, soluble, alpha 3 Entrez:2982  HGNC: 4685  HPRD: 00768  Ensembl: ENSG00000164116 
GUCY2Fguanylate cyclase 2F, retinal Entrez:2986  HGNC: 4691  HPRD: 02078  Ensembl: ENSG00000101890 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
GUCY1B3guanylate cyclase 1, soluble, beta 3
GUCY1A2guanylate cyclase 1, soluble, alpha 2
GUCY1A3guanylate cyclase 1, soluble, alpha 3
GUCY2Fguanylate cyclase 2F, retinal
Query geneGeneGene descriptionEdge score
HTR2CHTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
GUCY1B3GUCY1B3guanylate cyclase 1, soluble, beta 3
GUCY1A2GUCY1A2guanylate cyclase 1, soluble, alpha 2
GUCY1A3GUCY1A3guanylate cyclase 1, soluble, alpha 3
GUCY2FGUCY2Fguanylate cyclase 2F, retinal

Troyanskaya Laboratory - Princeton University