ASD

GO:0032321 positive regulation of Rho GTPase activity (55)

GeneInput weightStandardRank
SFRP1--204
RASGRF1--213
JUN--647
THY1--993
DLC1--1105
ARHGAP5--1129
NDEL10.2511194
GSK3B--1592
ARHGAP35--1706
TSC10.2511844
DOCK40.2512053
PREX1--2219
PREX2--2459
FZD10--2606
CDKL5--12680
RHOG--2753
SOS1--13181
PTK2B--3191
ARHGAP26--13447
ARHGAP1--3707
MYO9B--4244
ARHGAP6--4472
ARHGAP29--4961
FOXJ1--5202
ARAP3--6203
GRHL3--6732
CCL11--7037
ERRFI1--7414
PIN1--8222
TAX1BP3--8734
SYDE1--9488
RALBP1--10248
SYDE2--10285
CCL19--11890
ALS2--112325
ARHGAP8--12529
ARHGEF19--12571
EPHA2--114150
ARHGAP15--14909
OPHN10.5116404
CCL24--17974
CCL21--19130
CDC42EP2--19516
CCL26--19975
GPR65--20238
ARHGEF16--20461
DOCK7--20528
CCR7--21314
ARHGAP4--21597
GMIP--22058
ARHGEF10L--22238
NCKAP1L--23440
ARHGAP27--24221
SCRIB--24455
ARAP1--25493

Network

GO:0032321

Network
Enrichment
NameDescriptionExternal IDs
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1 Entrez:5923  HGNC: 9875  Ensembl: ENSG00000058335 
JUNjun proto-oncogene Entrez:3725  HGNC: 6204  HPRD: 01302  Ensembl: ENSG00000177606 
THY1Thy-1 cell surface antigen Entrez:7070  HGNC: 11801  HPRD: 01769 
DLC1deleted in liver cancer 1 Entrez:10395  HPRD: 05035  HGNC: 2897  Ensembl: ENSG00000164741 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SFRP1secreted frizzled-related protein 1
RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1
JUNjun proto-oncogene
THY1Thy-1 cell surface antigen
DLC1deleted in liver cancer 1
Query geneGeneGene descriptionEdge score
SFRP1SFRP1secreted frizzled-related protein 1
RASGRF1RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1
JUNJUNjun proto-oncogene
THY1THY1Thy-1 cell surface antigen
DLC1DLC1deleted in liver cancer 1

Troyanskaya Laboratory - Princeton University