ASD

GO:0042347 negative regulation of NF-kappaB import into nucleus (11)

GeneInput weightStandardRank
G3BP2--608
BMP7--987
FBXW11--1610
PSMD10--2012
NLRP30.2514091
CYLD--15851
NFKBIA--6067
IL10--17883
UACA--12262
NFKBIB--22383
FAF1--24152

Network

GO:0042347

Network
Enrichment
NameDescriptionExternal IDs
G3BP2GTPase activating protein (SH3 domain) binding protein 2 Entrez:9908  HPRD: 06570  HGNC: 30291  Ensembl: ENSG00000138757 
BMP7bone morphogenetic protein 7 Entrez:655  Ensembl: ENSG00000101144  HGNC: 1074  HPRD: 00212 
FBXW11F-box and WD repeat domain containing 11 Entrez:23291  Ensembl: ENSG00000072803  HPRD: 07294  HGNC: 13607 
PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 Entrez:5716  HPRD: 04594  HGNC: 9555  Ensembl: ENSG00000101843 
NLRP3NLR family, pyrin domain containing 3 Entrez:114548  HPRD: 05915  HGNC: 16400  Ensembl: ENSG00000162711 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
G3BP2GTPase activating protein (SH3 domain) binding protein 2
BMP7bone morphogenetic protein 7
FBXW11F-box and WD repeat domain containing 11
PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
NLRP3NLR family, pyrin domain containing 3
Query geneGeneGene descriptionEdge score
G3BP2G3BP2GTPase activating protein (SH3 domain) binding protein 2
BMP7BMP7bone morphogenetic protein 7
FBXW11FBXW11F-box and WD repeat domain containing 11
PSMD10PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
NLRP3NLRP3NLR family, pyrin domain containing 3

Troyanskaya Laboratory - Princeton University