ASD

GO:0032874 positive regulation of stress-activated MAPK cascade (14)

GeneInput weightStandardRank
MAPK8IP2--275
TGFB2--625
SEMA4C--1644
TAOK20.2512490
MID1--2525
TAOK3--4471
IL1A--4552
TAOK1--5452
IL1B--16220
IL26--10272
RIPK2--13928
CARD9--122070
NOD2--122677
NOD1--23711

Network

GO:0032874

Network
Enrichment
NameDescriptionExternal IDs
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2 Entrez:23542  HPRD: 09674  Ensembl: ENSG00000008735  HGNC: 6883 
TGFB2transforming growth factor, beta 2 Entrez:7042  HGNC: 11768  Ensembl: ENSG00000092969  HPRD: 01828 
SEMA4Csema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C Entrez:54910  Ensembl: ENSG00000168758  HGNC: 10731  HPRD: 07257 
TAOK2TAO kinase 2 Entrez:9344  HGNC: 16835  Ensembl: ENSG00000149930  HPRD: 18147 
MID1midline 1 (Opitz/BBB syndrome) Entrez:4281  Ensembl: ENSG00000101871  HGNC: 7095  HPRD: 02047 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2
TGFB2transforming growth factor, beta 2
SEMA4Csema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
TAOK2TAO kinase 2
MID1midline 1 (Opitz/BBB syndrome)
Query geneGeneGene descriptionEdge score
MAPK8IP2MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2
TGFB2TGFB2transforming growth factor, beta 2
SEMA4CSEMA4Csema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
TAOK2TAOK2TAO kinase 2
MID1MID1midline 1 (Opitz/BBB syndrome)

Troyanskaya Laboratory - Princeton University