ASD

GO:0060795 cell fate commitment involved in formation of primary germ layers (20)

GeneInput weightStandardRank
SOX2--1125
PAX2--459
NODAL--12184
SMAD1--2829
KLF4--3003
SOX17--3484
HOXA11--4215
EYA2--4403
NANOG--4730
WNT3A--4844
BMP4--15180
CTNNB10.2516229
SIX2--6713
WNT8A--7061
FOXC2--8308
TDGF1P3--9149
TRIM15--13912
FOXS1--15328
POU5F1--21422
FOXC1--122868

Network

GO:0060795

Network
Enrichment
NameDescriptionExternal IDs
SOX2SRY (sex determining region Y)-box 2 Entrez:6657  HGNC: 11195  HPRD: 08921  Ensembl: ENSG00000181449 
PAX2paired box 2 Entrez:5076  HGNC: 8616  Ensembl: ENSG00000075891  HPRD: 01330 
NODALnodal growth differentiation factor Entrez:4838  HGNC: 7865  HPRD: 08370 
SMAD1SMAD family member 1 Entrez:4086  Ensembl: ENSG00000170365  HGNC: 6767  HPRD: 03356 
KLF4Kruppel-like factor 4 (gut) Entrez:9314  HGNC: 6348  Ensembl: ENSG00000136826 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX2SRY (sex determining region Y)-box 2
PAX2paired box 2
NODALnodal growth differentiation factor
SMAD1SMAD family member 1
KLF4Kruppel-like factor 4 (gut)
Query geneGeneGene descriptionEdge score
SOX2SOX2SRY (sex determining region Y)-box 2
PAX2PAX2paired box 2
NODALNODALnodal growth differentiation factor
SMAD1SMAD1SMAD family member 1
KLF4KLF4Kruppel-like factor 4 (gut)

Troyanskaya Laboratory - Princeton University